Bartholin’s gland adenoma in a Saanen goat

Abstract

Tumors affecting Bartholin’s gland are considered rare in human medicine; there are few reports in the veterinary literature, with descriptions occurring only in cows. This article described the clinical and pathological findings associated with Bartholin’s gland adenoma in a goat. Clinically, a 7-year-old pregnant Saanen goat presented bilateral enlargement of the vulva that did not regress spontaneously after parturition. Grossly, these vulvar masses were multilobulated, contained cystic areas from which oozed a whitish fluid. Histopathology revealed an adenoma characterized by the proliferation of irregularly shaped neoplastic epithelial cells that formed tubular to glandular-like structures. These neoplastic cells demonstrated moderate anisokaryosis and evident nucleoli. The intratumoral proliferation index (PI) was estimated by immunoreactivity with the protein ki-67. Further, the glandular-like structures produced a Periodic Acid-Schiff positive secretion. A diagnosis of Bartholin’s gland adenoma was established due to the anatomic location of the neoplastic growths, the histopathological features, and the PI of the tumor.

Tumors of the reproductive tract of sheep and goats: A review of the current literature and a report of vaginal fibroma in an Awassi ewe

“…Three cases of leiomyoma (two uterine, one vagina) were reported in a large study involving 1146 necropsy or biopsy specimens from goats [11]. Uterine leiomyoma was also diagnosed in a dwarf goat with a history of chronic pollakisurie, tenesmus, and hydrometra [12].…”

“…Tumors of the Bartholin’s gland are usually classified as adenomas and carcinomas, with most of the tumors arising from either the mucin-secreting columnar epithelial cells or the squamous epithelium at the vestibular orifice of the gland [2]. In this review, only one case of adenoma of the Bartholin’s gland was diagnosed in a goat [12]. The doe was a 7-year-old pregnant Saanen goat with bilateral enlargement of the vulva [12].…”

“…In this review, only one case of adenoma of the Bartholin’s gland was diagnosed in a goat [12]. The doe was a 7-year-old pregnant Saanen goat with bilateral enlargement of the vulva [12]. Grossly, the tumor was involving the vulva with multilobulated cystic masses [12].…”

“…The doe was a 7-year-old pregnant Saanen goat with bilateral enlargement of the vulva [12]. Grossly, the tumor was involving the vulva with multilobulated cystic masses [12]. On histological evaluation, the tumor was characterized by proliferation of irregularly shaped, glandulotubular neoplastic epithelial cells [12].…”