Top-dressing 1% arginine supplementation in the lactation diet of sows does not affect the litter performance and milk composition

Dallanora, Djane; Walter, Marina; Marcon, Jessica; Saremba, Camila; Bernardi, Mari Lourdes; Wentz, Ivo; Bortolozzo, Fernando Pandolfo

doi:10.1590/0103-8478cr20141067

Cited by 5 publications

(1 citation statement)

References 19 publications

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“…However, Oksbjerg et al [ 14 ] reported an improved ADG from weaning to 140 kg of the pigs reared by sows supplemented with Arg during late gestation and lactation. On the other hand, Dallanora et al [ 81 ] and Krogh et al [ 13 ] reported that Arg supplementation during late gestation and lactation did not improve piglet performance.…”

Section: Discussionmentioning

confidence: 99%

Productive and physiological implications of top-dress addition of branched-chain amino acids and arginine on lactating sows and offspring

Luise

Correa

Stefanelli

et al. 2023

J Animal Sci Biotechnol

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Background Branched-chain amino acids (BCAAs), including L-leucine (L-Leu), L-isoleucine (L-Ile), L-valine (L-Val), and L-arginine (L-Arg), play a crucial role in mammary gland development, secretion of milk and regulation of the catabolic state and immune response of lactating sows. Furthermore, it has recently been suggested that free amino acids (AAs) can also act as microbial modulators. This study aimed at evaluating whether the supplementation of lactating sows with BCAAs (9, 4.5 and 9 g/d/sow of L-Val, L-Ile and L-Leu, respectively) and/or L-Arg (22.5 g/d/sow), above the estimated nutritional requirement, could influence the physiological and immunological parameters, microbial profile, colostrum and milk composition and performance of sows and their offspring. Results At d 41, piglets born from the sows supplemented with the AAs were heavier (P = 0.03). The BCAAs increased glucose and prolactin (P < 0.05) in the sows’ serum at d 27, tended to increase immunoglobulin A (IgA) and IgM in the colostrum (P = 0.06), increased the IgA (P = 0.004) in the milk at d 20 and tended to increase lymphocyte% in the sows’ blood at d 27 (P = 0.07). Furthermore, the BCAAs tended to reduce the Chao1 and Shannon microbial indices (P < 0.10) in the sows’ faeces. The BCAA group was discriminated by Prevotellaceae_UCG-004, Erysipelatoclostridiaceae UCG-004, the Rikenellaceae_RC9_gut_group and Treponemaberlinense. Arginine reduced piglet mortality pre- (d 7, d 14) and post-weaning (d 41) (P < 0.05). Furthermore, Arg increased the IgM in the sow serum at d 10 (P = 0.05), glucose and prolactin (P < 0.05) in the sow serum at d 27 and the monocyte percentage in the piglet blood at d 27 (P = 0.025) and their jejunal expression of NFKB2 (P = 0.035) while it reduced the expression of GPX-2 (P = 0.024). The faecal microbiota of the sows in Arg group was discriminated by Bacteroidales. The combination of BCAAs and Arg tended to increase spermine at d 27 (P = 0.099), tended to increase the Igs (IgA and IgG, P < 0.10) at d 20 in the milk, favoured the faecal colonisation of Oscillospiraceae UCG-005 and improved piglet growth. Conclusion Feeding Arg and BCAAs above the estimated requirements for milk production may be a strategy to improve sow productive performance in terms of piglet average daily gain (ADG), immune competence and survivability via modulation of the metabolism, colostrum and milk compositions and intestinal microbiota of the sows. The synergistic effect between these AAs, noticeable by the increase of Igs and spermine in the milk and in the improvement of the performance of the piglets, deserves additional investigation.

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Section: Discussionmentioning

confidence: 99%

Productive and physiological implications of top-dress addition of branched-chain amino acids and arginine on lactating sows and offspring

Luise

Correa

Stefanelli

et al. 2023

J Animal Sci Biotechnol

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Nutraceutical effect of minerals on performance, immunity, and antioxidant system of suckling piglets

et al. 2019

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Effect of dietary arginine-to-lysine ratio in lactation on biochemical indices and performance of lactating sows

Gao¹,

Wen²,

Guo³

et al. 2020

Journal of Animal Science

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The present study investigated the effect of optimizing the total dietary arginine-to-lysine ratios on metabolism of lactating sows and piglet performance by supplementation with L-arginine (Arg) during lactation. A total of 200 multiparous sows (3 to 6 parities, Yorkshire × Landrace) were selected and randomly and equally assigned to 5 groups in lactation, and finally 36, 34, 35, 36, and 33 dams completed the study in the dietary treatments, respectively, where the diets consisted of 5 step-up Arg-to-Lys ratios (0.9, 1.0, 1.1, 1.2, and 1.3) by the addition of 0, 0.10%, 0.20%, 0.30%, 0.40% Arg. The diets contained 3.37 to 3.38 Mcal of DE/kg energy, 17.73% to 17.75% crude protein (CP) and 0.98 to 1.01% Lys, and were fed ad libitum during lactation. The performance of sows and sucking piglets was measured, and plasma and milk samples were collected for analysis. The feed intake of sows as well as litter weight gain during lactation increased linearly (P ≤ 0.05) while maternal backfat and milk composition were not affected (P > 0.05) as the dietary Arg-to-Lys ratios increased. Analyzed plasma biochemical indices, including concentrations of free Arg, Orn and Glu, and prolactin, insulin, and follicle-stimulating hormone (FSH) responded linearly (P ≤ 0.05) to increases in dietary Arg-to-Lys ratios. The dietary Arg-to-Lys ratios of 1.01 and 1.02 were optimal for maternal feed intake and litter weight gain, based on broken-line models. Collectively, the results of this study indicate increasing total dietary Arg-to-Lys ratios in lactation was beneficial for the performance of lactating sows and sucking piglets, and dietary Arg-to-Lys ratios of 1.01 and 1.02 were optimal, from regression analyses, for the practical feeding of lactating sows.

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Top-dressing 1% arginine supplementation in the lactation diet of sows does not affect the litter performance and milk composition

Abstract: The study aimed to evaluate the effects of arginine supplementation in the lactation diet of sows on their milk composition, litter performance and piglet survival. Sixty

Cited by 5 publications

References 19 publications

Productive and physiological implications of top-dress addition of branched-chain amino acids and arginine on lactating sows and offspring

Productive and physiological implications of top-dress addition of branched-chain amino acids and arginine on lactating sows and offspring

Nutraceutical effect of minerals on performance, immunity, and antioxidant system of suckling piglets

Effect of dietary arginine-to-lysine ratio in lactation on biochemical indices and performance of lactating sows

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