Higher immunoexpression of CK14 from the Wnt-1/β-catenin pathway in the development of odontomas
Glória Maria de França,
Leonardo Magalhães Carlan,
Hévila de Figueiredo Pires
et al.
Abstract:Tooth development depends on a series of reciprocal signaling interactions between the oral epithelium and ectomesenchyme. This study aimed to investigate the role of CK14, a protein involved in Wnt-1/β-catenin signaling, in odontogenesis and the development of odontomas. This cross-sectional, retrospective, immunohistochemical study analyzed 30 compound odontomas, 30 complex odontomas, and 17 tooth germs. Higher immunoexpression of CK14 was observed in odontogenic epithelial cells of tooth germs (p < 0.001… Show more
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