Oral mucoceles: A Brazillian Multicenter Study of 1,901 Cases

Abstract

Oral mucocele (OM) is the most common lesion of minor salivary glands. The present study aimed to report the clinical and demographic features of a large series of OMs and identify possible predictive variables associated with the recurrence rate of these lesions. A retrospective descriptive cross-sectional study was performed. A total of 43,754 biopsy records from four pathology services in Brazil were analyzed. All cases of OMs were reviewed, and clinical and demographic data were collected. The study comprised 1,002 females (56.2%) and 782 males (43.8%), with a mean age of 19.8±16.4 years (range: 01-87 years) and a 1.3:1 female-to-male ratio. The lower lip (n=1,160; 67.4%), and floor of the mouth (n=172; 10.0%), were the most common affected sites, presenting clinically as nodules (n=978; 79.4%) of smooth surface (n=428; 77.5%) and normal color (n=768, 46.7%). Excisional biopsy was the treatment in most cases (n=1,392; 78.0%). Recurrent OMs represented 6.2% of all diagnosed cases (n=117). OMs recurred more commonly in younger patients (aged<20 years) (p<0.0001), in lesions larger than 2 cm in diameter (p<0.0001), and in those located in the ventral tongue (p=0.0351). Also, recurrence rates were higher significantly in cases treated with laser surgery than in those with conventional surgery (p=0.0005). Patients with OMs should be carefully informed of its possible recurrence, especially when found on the ventral tongue of young patients.

Ultrasonographic features of mass lesions in the oral submucosal epithelium using intraoral ultrasonography

“…Mucous cysts are the most common lesions arising from the salivary glands and are caused by salivary retention due to impaired salivary drainage 22–24 . Histopathologically, the cyst wall is composed of mucous granulation tissue, with no epithelial lining on the luminal surface.…”

“…Mucous cysts are the most common lesions arising from the salivary glands and are caused by salivary retention due to impaired salivary drainage. [22][23][24] Histopathologically, the cyst wall is composed of mucous granulation tissue, with no epithelial lining on the luminal surface. Because the lumen is filled with mucus, mainly saliva, ultrasonographic images showed a homogeneous, hypoechoic image inside the lesion, with posterior echo enhancement (Figure 4).…”

Manejo de lesões da mucosa oral relacionadas ao aparelho ortodôntico fixo

“…A mucocele é uma lesão comum da mucosa oral que ocorre devido à ruptura de um ducto de glândula salivar menor e extravasamento de mucina para o interior dos tecidos moles adjacentes [34][35] . Geralmente, a ruptura do ducto ocorre por trauma local, incidindo em crianças e jovens adultos, que estão mais propensos esse fator de risco 34 .…”

“…A mucocele é uma lesão comum da mucosa oral que ocorre devido à ruptura de um ducto de glândula salivar menor e extravasamento de mucina para o interior dos tecidos moles adjacentes [34][35] . Geralmente, a ruptura do ducto ocorre por trauma local, incidindo em crianças e jovens adultos, que estão mais propensos esse fator de risco 34 . Na ortodontia, os componentes do aparelho fixo podem ser os responsáveis pelo rompimento do ducto das glândulas salivares menores, especialmente da mucosa labial inferior que repousa sobre o aparelho.…”

“…As mucoceles possuem uma predileção importante pelo lábio inferior, se manifestando como um aumento de volume arredondado de até 2 mm, de coloração azulada, quando superficial, ou normocrômica, quando profunda [34][35] . A lesão pode ser flutuante ou firme a palpação, e geralmente está relacionada a um histórico de aumento de volume e rompimento e liberação do fluído na cavidade oral 34 . Mucoceles superficiais podem ocorrer ainda em ventre de língua, mucosa jugal e assoalho de boca.…”