Alkaline Peroxides Versus Sodium Hypochlorite for Removing Denture Biofilm: a Crossover Randomized Trial

Abstract

This study evaluated the efficacy of cleanser solutions on denture biofilm removal by a crossover randomized clinical trial. Thirty two edentulous patients were instructed to brush their dentures (specific brush and liquid soap) three times a day (after breakfast, lunch and dinner) and to soak them (≥ 8 h) in: (C) control -water; (AP): alkaline peroxide; or (SH) 0.5% sodium hypochlorite. Each solution was used for 21 days (three cycles of 7 days). At the end of each cycle, the inner surfaces of maxillary dentures were disclosed (1% neutral red) and photographed (HX1 - Sony). Areas (total and stained biofilm) were measured (Image Tool software) and the percentage of biofilm calculated as the ratio between the area of the biofilm multiplied by 100 and total surface area of the internal base of the denture. Data were compared by means of generalized estimating equation (α=5%) and multiple comparisons (Bonferroni; α=1.67%). Immersion in SH reduced biofilm (%) (8.3 ± 13.3B) compared to C (18.2 ± 14.9A) and AP (18.2 ± 16.6A). The 0.5% sodium hypochlorite solution was the most efficacious for biofilm removal. Alkaline peroxides may not lead to further biofilm removal in patients with adequate denture maintenance habits.

Evaluation of biofilm removal and adverse effects on acrylic resin by diluted concentrations of sodium hypochlorite and Ricinus communis solutions

“…The 1% solution was effective; however, this concentration may result in adverse effects on acrylic resin in short and long periods of immersion. The 0.5% solution was also effective in periods of 20 minutes and 8 hours . Therefore, recent clinical trials have been conducted to verify the effectiveness of the diluted concentrations of sodium hypochlorite on biofilm control.…”

“…The patient has the responsibility to maintain good oral hygiene conditions, and the dentist must motivate and instruct the patient about denture and oral hygiene, guiding an effective biofilm control by appropriate methods; however, these steps are neglected . Combination of mechanical and chemical methods is the most significant method for denture hygiene owing to the ability to remove biofilm (mechanical method) and show antimicrobial action (chemical solution) …”

Effect of Alkaline Peroxide-type Denture Cleaners to the Microbial Profile in Maxillary Complete Denture

“…Alkaline peroxides were shown to be effective on newly-formed plaque and stains. 9 With the current rising number of the elderly, the demand for dentures has been increasing dramatically over the years. Thus, a denture hygiene procedure is of paramount importance to denture wearers.…”

“…[2][3][4]9 Therefore, a soft bristle toothbrush was used to remove the debris and deposit it mechanically from the denture, followed by immersion of the denture in alkaline peroxide-typed denture cleansers. However, the intention of this study was to test the efficacy of various brands of peroxide-type denture cleansers on microbials on dentures.…”

“…Some studies have reported their ineffectiveness on biofilm removal while others have demonstrated otherwise. 9 Alkaline peroxides usually are the choice due to their good antimicrobial activity against denture biofilms in the absence of odor and aftertaste.…”