Biliary Complications After Liver Transplantation

Coelho, J. C. U.; Leite, Lucas de Oliveira; Molena, Antonio; Freitas, Alexandre Coutinho Teixeira de; Matias, Jorge Eduardo Fouto

doi:10.1590/0102-6720201700020011

Cited by 17 publications

(23 citation statements)

References 23 publications

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“…In this context, according to the work of Coelho et al [2], 153 (84.1%) deceased donors and 29 (15.9%) live donor transplants were performed. Biliary complications occurred in 49 patients (26.9%): 28 stenoses (15.4%), 14 leaks (7.7%) and seven leaks followed by stenoses (3.85%).…”

Section: Discussionmentioning

confidence: 99%

“…Biliary complications after hepatic transplantation have a variable incidence of 10 to 25% of all complications after hepatic transplantation and mortality reported in up to 10%, has an important impact on the quality of life of the patient [1], in the first year after transplantation, with progressive reduction of frequency after 1 year [1,2]. Complications can be early, those occurring in the first month or late when they occur after the first month.…”

Section: Introductionmentioning

confidence: 99%

“…Complications can be early, those occurring in the first month or late when they occur after the first month. Among the possible bile complications, bile duct stenosis is the most common, representing 40% of all of them [2,3]. In Brazil, it occurred in São Paulo in 1985 and, currently, the country is third in the world in absolute number of transplants, after the United States and China [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…In this scenario, bile reconstitution is one of the main challenges of liver transplantation, since biliary complications remain the most frequent postoperative technical complication [1, 2,7]. Biliary complications have a high incidence, increase hospitalization time and hospital costs, as well as patient mortality [8].…”

Section: Introductionmentioning

confidence: 99%

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Epidemiologic Study on the Incidence of Biliary Complications after Liver Transplantation

Silva¹,

Andrade²,

Lisboa³

et al. 2018

J Liver

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Introduction: Biliary complications after hepatic transplantation have a variable incidence of 10 to 25% among all complications after hepatic transplantation and mortality reported up to 10%, have an important impact on the patient's quality of life, since it implies the need for hospitalizations and multiple interventions for treatment. They are more frequent in the first year after transplantation, with progressive reduction of the frequency after 1 year. Objective: To evaluate the risk factors of greater impact in the development of bile duct stenosis in patients after liver transplantation. Methods: One hundred and eighty-eight charts of liver transplant patients were retrospectively evaluated. Inclusion criteria: liver transplanted patients from 2011 to December 2017. Exclusion criteria: deaths that occurred between the first month after transplantation, incomplete medical records and most cases of retransplants, except for patients who retransplanted as a consequence of their own complication. Results: Biliary complications were present in 14% (N=26) of the patients. Of these, 52% (N=21) presented stenosis of the biliary tract, followed by other complications such as cholangitis (20%), fistula calculation (10%), bilioma (3%). Among patients with bile duct stenosis, 19% (N=4) presented non-anastomotic stenosis and 81% (N=17) anastomotic stenosis. The cause of hepatopathy was in 42% of patients (N=9) ethanolic, followed by other causes such as: viral hepatitis, cryptogenic, autoimmune, fulminant hepatitis, NASH, CEP, glycogenosis and 1 case of secondary retransplantation to the bile complication itself. Conclusion: The incidence of biliary complications is comparable with the incidence reported in other institutions. The low incidence of bile duct stenosis reduces the power of the study to identify the most impacting risk factors.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiologic Study on the Incidence of Biliary Complications after Liver Transplantation

Silva¹,

Andrade²,

Lisboa³

et al. 2018

J Liver

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“…The incidence of biliary complications has decreased dramatically because of advances in liver transplantation; however, biliary complication remains the most frequent complications postliver transplantation, with an incidence of 26.92-53.8% [55,56]. Biliary complication is no longer a major cause of mortality in experienced liver transplantation center, as these complications can be recognized early and revive timely effective management.…”

Section: Biliary Complicationsmentioning

confidence: 99%

Liver Transplantation in China

Ming¹,

Zhuang²,

Tu³

et al. 2019

Surgical Challenges in the Management of Liver Disease

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Liver transplantation has been developed in Mainland China for about 40 years, from clinical trials to maturity. Its number has become the second in the world, its quality is also in line with the international level, and the source of donors has gradually transitioned to donation after citizen's death (DCD). This chapter is aimed to elaborate the liver transplant work in China from the history and current status of liver transplantation, the main operating methods, major indications, donor maintenance and donor quality assessment, postoperative major complications, and application of immunosuppressive agents to the postoperative follow-up. Liver transplantation is a meaningful and challenging work currently in China; all the Chinese transplant surgeons and scholars are devoting themselves to this work in order to give more effective help to the patients.

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