In-hospital adverse drug events: analysis of trend in Portuguese public hospitals

Vitorino, Mavilde; Aguiar, Pedro; Sousa, Paulo

doi:10.1590/0102-311x00056519

Cited by 6 publications

(2 citation statements)

References 25 publications

(59 reference statements)

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“…In Portugal, the magnitude, typologies, and nature of adverse events (AE) have been characterized in studies developed during the last decade. Some of those studies focused on a specific type of AE (related to medication) [25,26] and others analyzed all types of AE [23,27].…”

Section: Introductionmentioning

confidence: 99%

Contributions to the Portuguese National Plan for Patient Safety 2021–2026: A Robust Methodology Based on the Mixed-Method Approach

Sousa

Paiva

Lobão

et al. 2021

Port J Public Health

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Introduction: Several countries prioritize patient safety in their health policies. In Portugal, following the implementation of the National Plan for Patient Safety (NPPS) 2015–2020, the research team of the National School of Public Health (NSPH) carried out extensive work to continue improving aspects of the previous Plan. This work was focused on identifying the strengths and weaknesses of NPPS 2015–2020 and aspects related to its applicability and main challenges and opportunities for the implementation of the NPPS 2021–2026. Methods: Methodological dynamic process was based on the most relevant international and national guidelines and the feedback from key patient safety stakeholders. We developed a cross-sectional mixed-methods study from January to August 2021. We used documentation and periodical reports from National Health Service (NHS) healthcare institutions as secondary sources of information. For primary data collection, we used an online survey (applied to elements in the different quality and safety structures of hospitals and primary care units), interviews, and focus groups to collect information from patient safety experts. Results and Discussion: Strengthening safety culture, patient safety training, communication, leadership involvement, patient and family engagement, and monitorization process is considered essential. We also identified local limitations such as the lack of resources and protected time for the healthcare professionals and lack of leadership involvement on patient safety strategies for dedicating to patient safety actions. Most of the patient safety stakeholders agreed that the safety and health of clinical teams and new modalities of healthcare (such as telemedicine, home hospitalization, home care) should be a priority for patient safety strategies. Conclusions: In our study, we used a robust methodology with a participatory process involving different stakeholders. An alignment between local, regional, and national levels in terms of measuring indicators, the definition of priorities, and actions and activities to improve patient safety is recommended. Reinforced partnerships and alignment between the institution’s mission, and safety priorities will be crucial to enhance patient safety. Additionally, this work highlights the added value for health systems achieved through strong partnerships between public administration and academic institutions to improve healthcare quality and patient safety.

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Section: Introductionmentioning

confidence: 99%

Contributions to the Portuguese National Plan for Patient Safety 2021–2026: A Robust Methodology Based on the Mixed-Method Approach

Sousa

Paiva

Lobão

et al. 2021

Port J Public Health

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“…A recent study in public hospitals in Portugal (5) , a second one in China (6) and a third one in the ICU of a tertiary public hospital in the Brazilian Midwest (1) showed that more than 60% of in-hospital patients suffered from at least one ADE, many of which are preventable (1) . Molina and colleagues, in a retrospective descriptive study performed in a 12-bed university ICU found that 52,1% of the individuals presented at least one AE, and almost half of them were considered preventable (7) .…”

Section: Introductionmentioning

confidence: 99%

Performance of the trigger tool methodology in the identification of adverse drug events in intensive care / Desempenho da metodologia trigger tool na identificação de eventos adversos a medicamentos em unidade intensiva

Agrizzi¹,

Castilho²

2021

Braz. J. Hea. Rev.

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Adverse drug events (ADE) may increase the length of hospital stay, cause complications in the patient's clinical condition, contribute to death and increase hospital costs. The aim of this study was to apply the trigger tool methodology based on the method proposed by the Institute for Healthcare Improvement for the detection of adverse drug events in an intensive care unit, assessing the incidence of event and the feasibility of incorporating this practice into the unit. After the development of a trigger list, a retrospective review was carried out on a random sample of 10 patient records / month, among patients over 18 years of age, of both sexes, who were hospitalized in the intensive care unit of the study hospital. The incidence of patients with adverse drug events was 15%, and the rate of ADE was 15.8 ADE / 100 medical records, with most (85%) of the events categorized as temporary damage requiring intervention. The main therapeutic classes involved in adverse events were antibiotics, anticoagulants, sedatives and hypoglycemic agents. The main advantage of the methodology was the ability to detect more adverse drug events than the voluntary notification, methodology present at the institution at that time.

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Hospitalizations and deaths related to adverse drug events worldwide: Systematic review of studies with national coverage

Silva

Modesto

Amaral

et al. 2021

Eur J Clin Pharmacol

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In-hospital adverse drug events: analysis of trend in Portuguese public hospitals

Cited by 6 publications

References 25 publications

Contributions to the Portuguese National Plan for Patient Safety 2021–2026: A Robust Methodology Based on the Mixed-Method Approach

Contributions to the Portuguese National Plan for Patient Safety 2021–2026: A Robust Methodology Based on the Mixed-Method Approach

Performance of the trigger tool methodology in the identification of adverse drug events in intensive care / Desempenho da metodologia trigger tool na identificação de eventos adversos a medicamentos em unidade intensiva

Hospitalizations and deaths related to adverse drug events worldwide: Systematic review of studies with national coverage

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