Quimioterapia Aerossolizada e Pressurizada Intraperitoneal (PIPAC) por monoportal: aplicação alternativa no controle das metástases peritoneais.

Abstract

Peritoneal carcinomatosis is the natural course of gastrointestinal, gynecologic, and primary peritoneal neoplasms. In recent years, our understanding of carcinomatosis has changed; it is no longer considered a disseminated condition, but rather a disease confined to the peritoneum. Thus, the combination of cytoreductive surgery and intraperitoneal chemotherapy has become the cornerstone of control of peritoneal metastases. Traditionally, intraperitoneal chemotherapy is delivered in the form of liquid solutions. However, a new mode of chemotherapy delivery to the abdominal cavity has arisen as an alternative to the conventional method. In Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC), the liquid solution is aerosolized into a spray, potentiating the distribution and penetration of the chemotherapeutic agent intraperitoneally. The present study aims to describe a novel form of this innovative surgical technique performed for the first time in Brazil, in a modification of the technique originally described for PIPAC: delivery through a single-port device.

Considerações da Sociedade Brasileira de Oncologia Cirúrgica (SBCO) sobre o manejo de malignidades da superfície peritoneal durante a pandemia de COVID-19

“…[9] In Brazil, these precautions were no different. [10] This peculiarity of the technique adds a theoretical advantage in the exposure of the surgical team to COVID-19 compared to laparoscopy. However, in an atypical period such as the current scenario of COVID-19 pandemic, PIPAC, together with other oncological treatments, must be adapted to the reality of the epidemiological period.…”