Effects of local pressure on cutaneous blood flow in pigs

Abstract

Objective: to evaluate the effects of increasing pressures on the cutaneous blood flow in the skin of pigs. Methods: we conducted an experimental study in pigs submitted to subcutaneous magnetic implants (n=30). After healing, were applied external magnets with varying magnetic forces to the skin, generating compression. We evaluated the cutaneous circulation of the skin under compression by the Laser Speckle Contrast Imaging (LSCI) technique. We measured the depth of the implants by ultrasonography, and applied computational simulations to the calculation of the different pressure values, considering the different distances between implants and external magnets. Results: nineteen implants presented complications. The remaining 11 were submitted to different magnetic compression forces and perfusion analysis. Two linear regression models showed an inverse correlation between exerted pressure and cutaneous perfusion, with significant variation, mainly in the initial pressure increases, of up to 20mmHg. Conclusion: The main reduction in cutaneous blood flow resulted from initial increases of up to 20 mmHg. The results suggest that tissue ischemia can occur even in low-pressure regimes, which could contribute to the appearance of skin lesions, particularly ulcers related to medical devices.

Wound Physiology and Experimental Wound Models: Traditional Review

“…İkinci olarak, mıknatıs normal derinin üzerine değil de zaten hasarlı olan kesik derinin altına yerleştirilmektedir. 75…”

Does Trans-Radial Longitudinal Compression Influence Myoelectric Control?

“…29,31 If the pressure restricts blood flow for a significant period of time, wounds, injuries and even tissue death can occur. 20,31,[32][33][34] Finding an acceptable level of compression and blood perfusion is a complex task for prosthetists without additional equipment. 20 No quantitative method or guidelines are available, however postischaemic hyperemia (redness after a prosthesis is removed) can be used to gauge acceptable compression levels.…”

“…33 Additionally, the safe range for compression garments depend on the location compression is being applied to. 29,31,[32][33][34][35] Similarly, studies of localised pressure often refer to pressure sores resulting from long-term tissue ischaemia in immobile patients. 29,35 This study explored the potential effect of longitudinal compression on three fundamental factors central to the use of myoelectric prostheses; namely, control, electrode-skin contact and muscle fatigue.…”