Chest computed tomography to evaluate lymphocytic interstitial pneumonia

Barreto, Míriam Menna; Rodrigues, Rosana Souza

doi:10.1590/0100-3984.2020.53.5e1

Cited by 3 publications

(2 citation statements)

References 10 publications

(9 reference statements)

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“…Recent studies conducted in Brazil have highlighted the importance of imaging examinations, especially CT, to improving the diagnosis of pulmonary diseases ( 17 - 21 ) . To our knowledge, this is the first study to investigate insufflated specimens by postoperative CT to identify nodules and predict tumor-free margins, with subsequent histopathology correlation.…”

Section: Discussionmentioning

confidence: 99%

Postoperative computed tomography of insufflated lung specimens obtained by video-assisted thoracic surgery: detection and margin assessment of pulmonary nodules

et al. 2022

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Objective: To investigate the utility of computed tomography (CT) scans to detect and assess the margin status of pulmonary nodules that were insufflated after being resected by video-assisted thoracic surgery. Materials and Methods: This was a novel multicenter study conducted at two national referral centers for thoracic diseases. Patients suspected of having lung cancer underwent video-assisted thoracic surgery for the resection of pulmonary nodules, which were submitted to postoperative CT. Measurements from the CT scans were compared with the results of the histopathological analysis. Results: A total of 37 pulmonary nodules from 37 patients were evaluated. The mean age of the patients was 65 years (range, 36-84 years), and 27 (73%) were female. A CT analysis of insufflated specimens identified all 37 nodules, and 33 of those nodules were found to have tumor-free margins. The histopathological analysis revealed lung cancer in 30 of the nodules, all with tumor-free margins, and benign lesions in the seven remaining nodules. Conclusion: Postoperative CT of insufflated suspicious lung lesions provides real-time detection of pulmonary nodules and satisfactory assessment of tumor margins. This initial study shows that CT of insufflated lung lesions can be a valuable tool at centers where intraoperative histopathological analysis is unavailable.

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Section: Discussionmentioning

confidence: 99%

Postoperative computed tomography of insufflated lung specimens obtained by video-assisted thoracic surgery: detection and margin assessment of pulmonary nodules

et al. 2022

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“…HRCT allows for establishing the extent of disease, identifying pleural or mediastinal/hilar involvement, and for differentiating LIP from other diffuse pulmonary diseases [83,87]. The classic HRCT findings are GGO, poorly defined central lobular and subpleural nodules, thickening of the bronchovascular bundles, interlobular septal thickening, thin-walled cystic airspaces (notably with perivascular distribution), and lymph node enlargement (Figure 8); less common findings are large nodules, emphysema, airspace consolidation, bronchiectasis, architectural distortion, honeycombing, and pleural thickening [79,88].…”

Section: Diagnosismentioning

confidence: 99%

Noninfectious Granulomatous Lung Disease: Radiological Findings and Differential Diagnosis

Lassandro,

Picchi,

Corvino

et al. 2024

JPM

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Granulomatous lung diseases (GLDs) are a heterogeneous group of pathological entities that can have different clinical presentations and outcomes. Granulomas are histologically defined as focal aggregations of activated macrophages, Langerhans cells, and lymphocytes, and may form in the lungs when the immune system cannot eliminate a foreign antigen and attempts to barricade it. The diagnosis includes clinical evaluation, laboratory testing, and radiological imaging, which especially consists of high-resolution computed tomography. bronchoalveolar lavage, transbronchial needle aspiration or cryobiopsy, positron emission tomography, while genetic evaluation can improve the diagnostic accuracy. Differential diagnosis is challenging due to the numerous different imaging appearances with which GLDs may manifest. Indeed, GLDs include both infectious and noninfectious, and necrotizing and non-necrotizing granulomatous diseases and the imaging appearance of some GLDs may mimic malignancy, leading to confirmatory biopsy. The purposes of our review are to report the different noninfectious granulomatous entities and to show their various imaging features to help radiologists recognize them properly and make an accurate differential diagnosis.

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