Contribution of dynamic contrast enhancement and diffusion-weighted magnetic resonance imaging to the diagnosis of malignant cervical lymph nodes

Wolosker, Ângela Maria Borri

doi:10.1590/0100-3984.2018.51.3e3

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…Benign nodes in our patient population may therefore have different diffusion characteristics to normal or reactive nodes in the general population without elevated EBV levels. To note, a few prior studies have reported lower mean ADC values in benign compared with malignant nodes [44][45][46][47], and Cintra et al [47] speculated that the underlying pathological cause of benign nodes influences their diffusion values. Moreover, it is well established that diffusion parameters of malignant nodes may also vary according to the underlying pathology, with significant differences found amongst malignant nodes for NPC, SCC and lymphoma [48].…”

Section: Discussionmentioning

confidence: 99%

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes

Lam

et al. 2020

Neuroradiology

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Purpose Anatomical imaging criteria for the diagnosis of malignant head and neck nodes may not always be reliable. This study aimed to evaluate the diagnostic value of conventional diffusion-weighted imaging (DWI) and intravoxel incoherent motion (IVIM) DWI in discriminating benign and malignant metastatic retropharyngeal nodes (RPNs). Methods IVIM DWI using 14 b-values was performed on RPNs of 30 patients with newly diagnosed metastatic nasopharyngeal carcinoma (NPC) and 30 patients with elevated plasma Epstein-Barr virus (EBV)-DNA without NPC who were part of an EBV-based NPC screening program. Histogram measurements of the two groups were compared for pure diffusion coefficient (D), pseudo-diffusion coefficient (D*), perfusion volume fraction ( f ) and apparent diffusion coefficient (ADC) using the Mann-Whitney U test. Area under the curves (AUCs) of significant measurements were calculated from receiver-operating characteristics analysis and compared using the DeLong test. Results Compared with metastatic RPNs, benign RPNs had lower ADC mean (0.73 vs 0.82 × 10 −3 mm 2 /s) and D mean (0.60 vs 0.71 × 10 −3 mm 2 /s) and a higher D* mean (35.21 vs 28.66 × 10 −3 mm 2 /s) (all p < 0.05). There was no difference in the f measurements between the two groups (p = 0.204 to 0.301). D mean achieved the highest AUC of 0.800, but this was not statistically better than the AUCs of the other parameters (p = 0.148 to 0.991). Conclusion BenignRPNs in patients with EBV-DNA showed greater restriction of diffusion compared with malignant metastatic RPNs from NPC. IVIM did not show a significant advantage over conventional DWI in discriminating benign and malignant nodes. Keywords Diffusion magnetic resonance imaging . Head and neck . Nasopharyngeal carcinoma . Lymph nodes . Epstein-Barr virus . Retropharyngeal node . Benign and malignant Abbreviations ADC Apparent diffusion coefficient AUC Area under the curve * Qi-Yong H. Ai

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Section: Discussionmentioning

confidence: 99%

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes

Lam

et al. 2020

Neuroradiology

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“…Recent advances in computed tomography (CT) and magnetic resonance imaging techniques have increased the importance of imaging studies in the evaluation of diseases that affect the head and neck ( 5 - 10 ) . Although CT scans are used routinely in anatomical evaluations of the paranasal sinuses, a recent study showed that 75% of radiological reports add little value in terms of informing therapeutic decisions ( 1 , 11 ) .…”

Section: Introductionmentioning

confidence: 99%

Preoperative computed tomography evaluation of the paranasal sinuses: what should the physician know? - pictorial essay

2019

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The introduction of functional endoscopic sinus surgery in the 1980s brought about a drastic change in the treatment of patients with rhinosinusitis, improving quality of life through the removal of pathological processes or anatomical variations that obstruct the drainage pathways of the paranasal sinuses. However, despite the routine use of computed tomography in the anatomical evaluation of the paranasal sinuses, most radiological reports still do not provide sufficient information to guide the surgical planning. The objective of this pictorial essay was to demonstrate, through computed tomography, the main anatomical variations of the paranasal sinuses, the recognition of which is fundamental for preoperative planning, in order to avoid treatment failure and iatrogenic complications.

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Agreement between diagnostic imaging methods for the evaluation of lymphadenopathies in HIV-infected/AIDS patients

et al. 2019

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ObjectiveTo assess the percent agreement between diagnostic imaging modalities for the evaluation of lymphadenopathies in HIV-infected/AIDS patients.Materials and MethodsThis was an open, comparative, prospective study of diagnostic imaging methods for lymphadenopathy evaluation. We evaluated 30 patients (19 men and 11 women). All underwent ultrasound and computed tomography (CT). Twenty of the patients also underwent magnetic resonance imaging (MRI). We determined the percent agreement between two examiners using the various imaging methods to evaluate lymphadenopathies.ResultsCT had the highest percent agreement, at 93.3%, with a kappa coefficient of 0.85, corresponding to 28 of the 30 examinations. When we compared the percent agreement between the two examiners and between CT and ultrasound, examiner 1 had an observed rate of 80.0%, with a kappa of 0.49, corresponding to 24 of the 30 examinations, whereas examiner 2 had a rate of 70.0%, with a kappa of 0.31, corresponding to 21 of the 30 examinations. Between MRI and CT, the percent agreement for examiner 1 was 50.0%, with a kappa of −0.18, corresponding to 10 of the 20 examinations, whereas that for examiner 2 was 85.0%, with a kappa of 0.69, corresponding to 17 of the 20 examinations. For MRI and ultrasound, examiner 1 had a percent agreement of 70.0%, with a kappa of 0.20, corresponding to 14 of the 20 examinations, and examiner 2 had a percent agreement of 75.0%, with a kappa of 0.38, corresponding to 15 of the 20 examinations.ConclusionThis study indicates that intermethod agreement is highly dependent on the way in which the research is conducted, rather than on the level of experience of the examiner.

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Contribution of dynamic contrast enhancement and diffusion-weighted magnetic resonance imaging to the diagnosis of malignant cervical lymph nodes

Cited by 4 publications

References 8 publications

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes

Preoperative computed tomography evaluation of the paranasal sinuses: what should the physician know? - pictorial essay

Agreement between diagnostic imaging methods for the evaluation of lymphadenopathies in HIV-infected/AIDS patients

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