Chest computed tomography in bronchiolitis obliterans after bone marrow transplantation

Hochhegger, Bruno; Baldisserotto, Matteo

doi:10.1590/0100-3984.2017.50.3e3

Cited by 2 publications

(3 citation statements)

References 13 publications

(8 reference statements)

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“…Most recent articles about thoracic radiology in infectious diseases address aspects of CT ( 8 - 11 ) . However, chest X-ray still plays an important role, especially in pediatric patients ( 12 ) .…”

Section: Discussionmentioning

confidence: 99%

“…In relation to the distance from the hilum, the findings were categorized as central (within 4 cm of the hilum), peripheral, or peribronchial. The extent of the findings was categorized as either less than 25% or greater than 25% ( 8 ) . In addition, the lungs were segmented into upper, middle, and lower zones by using imaginary horizontal lines dividing the lungs into those three levels, each zone representing one third of the long axis of each lung.…”

Section: Methodsmentioning

confidence: 99%

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Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection

et al. 2019

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Objective: To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection. Materials and Methods: We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by polymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death. Results: The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029). Conclusion: In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection

et al. 2019

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“…Inflammation and fibrosis of terminal bronchioles causes narrowing and/or complete obliteration of the airway lumen, leading to chronic airflow obstruction. 1 , 2 , 3 , 4 , 5 , 6 , 7 These anatomofunctional changes can result in progressive loss of strength/endurance of ventilatory muscles, directly contributing to the reduction in activities of daily living (ADLs), with a consequent negative impact on exercise tolerance. 8 …”

Section: Introductionmentioning

confidence: 99%

Exercise Capacity in Children and Adolescents With Post-Infectious Bronchiolitis Obliterans: A Systematic Review

Rodrigues

Schiwe

Campos

et al. 2019

Rev. paul. pediatr.

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Objective: To evaluate exercise capacity in children and adolescents with post-infectious bronchiolitis obliterans. Data source: This is a systematic review based on data from PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (SciELO), and Physiotherapy Evidence Database (PEDro). We used the following search strategy: “Exercise capacity OR Exercise Test OR Physical fitness OR Functional capacity OR Six-minute walk test OR Shuttle walk test OR Cardiopulmonary exercise test AND Bronchiolitis obliterans.” We selected studies that evaluated exercise capacity through maximal/submaximal testing in children and adolescents with post-infectious bronchiolitis obliterans, and no other associated disease. We searched articles in English, Portuguese, and Spanish, without restrictions regarding the period of publication. The methodological quality was assessed by the Agency for Healthcare Research and Quality (AHRQ) protocol. Data synthesis: Out of the 81 articles found, only 4 were included in this review. The studies totaled 135 participants (121 with post-infectious bronchiolitis obliterans and 14 healthy), with sample sizes between 14 and 58 subjects. All patients underwent spirometry to evaluate pulmonary function, indicating an obstructive ventilatory pattern. Among them, 3/4 had their physical performance assessed by the six-minute walk test and 2/4 by the cardiopulmonary exercise testing. These test results were compared to those of a control group (1/4) and presented as percentage of predicted and/or in meters (3/4). Lastly, 3/4 of the studies showed reduced exercise capacity in this population. The studies included were classified as having high methodological quality. Conclusions: Findings of the study demonstrate that children and adolescents with post-infectious bronchiolitis obliterans have reduced exercise capacity.

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Chest computed tomography in bronchiolitis obliterans after bone marrow transplantation

Cited by 2 publications

References 13 publications

Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection

Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection

Exercise Capacity in Children and Adolescents With Post-Infectious Bronchiolitis Obliterans: A Systematic Review

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