Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites
Cleyson Mathias Morais Delvoss,
Alexandre Haruo Inoue,
Rosiane Valeriano da Silva
et al.
Abstract:BACKGROUND
Conventional microscopic counting is a widely utilised method for evaluating the trypanocidal effects of drugs on intracellular amastigotes. This is a low-cost approach, but it is time-consuming and reliant on the expertise of the microscopist. So, there is a pressing need for developing technologies to enhance the efficiency of low-cost anti-
Trypanosoma cruzi
drug screening.
OBJECTIVES
In our laboratory, we aimed to expedite the s… Show more
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