Lipid droplets in Zika neuroinfection: Potential targets for intervention?
Suelen Silva Gomes Dias,
Tamires Cunha-Fernandes,
Vinicius Cardoso Soares
et al.
Abstract:Lipid droplets (LD) are evolutionarily conserved lipid-enriched organelles with a diverse array of cell- and stimulus-regulated proteins. Accumulating evidence demonstrates that intracellular pathogens exploit LD as energy sources, replication sites, and part of the mechanisms of immune evasion. Nevertheless, LD can also favor the host as part of the immune and inflammatory response to pathogens. The functions of LD in the central nervous system have gained great interest due to their presence in various cell … Show more
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