Seroprevalence and risk factors associated with canine visceral leishmaniasis in the State of Paraíba, Brazil

Silva, Raizza Barros Sousa; Porto, Maurina Lima; Barbosa, Werona de Oliveira; Souza, Heitor Cândido de; Marques, Nedja Fernanda Dos Santos Pinto; Azevêdo, Sérgio Santos de; Andrade, Paulo; Melo, Márcia Almeida de

doi:10.1590/0037-8682-0429-2017

Cited by 12 publications

(13 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, R . sanguineus presence was associated with anti- Leishmania antibodies as it was reported by Silva et al (2018 [54]), but repellent could have an effect on tick control, since in 2014 there was a significant negative association between the use of repellent and the presence of ticks (z = -4,646, p = 0.0383). This year, the use of repellent was higher and the number of dogs infested with ectoparasites was lower than in 2018.…”

Section: Discussionsupporting

confidence: 61%

Twice upon a time: The progression of canine visceral leishmaniasis in an Argentinean city

et al. 2019

View full text Add to dashboard Cite

Canine Visceral Leishmaniasis (CVL) prevalence, spatial distribution and associated factors were assessed in four locations in Iguazú department in 2014 and in Puerto Iguazú city again in 2018. The city areas were divided into a grid of 400x400m cells. All cells were sampled in 2014 and a random subsampling was developed in 2018. In each cell, five dogs clustered in a ‘critical scenario’ (prone to have vectors) were sampled. A rapid immunochromatographic dipstick was used to detect antibodies against Leishmania infantum , confirming by lymph node smears observation and PCR. For Puerto Iguazú, Generalized Linear Models (GLMs) were constructed considering environmental, dog and clinical variables. Pearson's Chi square and Fisher's exact tests were employed to evaluate the association between CVL, dog clinical signs and infestation with other parasites. Cartographic outputs were made and Moran's I indices were calculated as spatial autocorrelation indicators. CVL prevalence rates were 26.18% in 2014 and 17.50% in 2018. No associations were established in environmental models, but dog age and repellent use were significant when running 2014 dog models. Clinical models showed significant associations between seropositive dogs and ophthalmological, dermal signs and onychogryphosis in 2014. In 2018, only adenomegaly was associated. The results of global Moran´s I were not significant but regarding local analysis, six sites in 2014 and one in 2018 presented autocorrelation with neighboring sites. The decrease in CVL prevalence may be associated to transmission stabilization, which could explain the lack of associations with dog-related variables. Further, spatial distribution of CVL is a poor evidence for design of transmission control measures but could be important in case of intensive parasite circulation or when the first autochthonous cases appear. For control success, sensitivity of diagnostic methods, political will and adequate material resources remain critical. Modeling of multiple variables will be required to identify factors that drive disease stabilization/destabilization.

show abstract

Section: Discussionsupporting

confidence: 61%

Twice upon a time: The progression of canine visceral leishmaniasis in an Argentinean city

et al. 2019

View full text Add to dashboard Cite

show abstract

“…In João Pessoa, capital of Paraíba, the seroprevalence of CL was much lower (5.90%) (Fernandes et al, 2016). In the hinterland of Paraíba, seroprevalence was 20.00% in Cajazeiras, 16.30% in Uiraúna and 10.50% in Sousa (Silva et al, 2018). In Patos, a municipality far 44 km from Santa Luzia, has a similar data, with a prevalence of 18.40% in the urban area (Fernandes et al, 2016) and 11.33% in the rural area (Silva et al, 2016).…”

Section: Discussionmentioning

confidence: 67%

Spatial analysis of canine leishmaniasis in an area of transmission of the semi-arid region of the State of Paraíba, Brazil

Silva

Franco-Silva

Lima

et al. 2021

Rev. Bras. Parasitol. Vet.

Self Cite

View full text Add to dashboard Cite

Visceral leishmaniasis is a widely distributed zoonosis and canine infection is an important indicator of risk for the occurrence of the disease in humans. The goal of this analysis was to study the spatial clustering of canine leishmaniasis (CL) in the municipality of Santa Luzia, state of Paraíba. For this, 749 samples of canine plasma were tested using three serological tests. The dog was considered positive if it reacted in two serological tests. The location of the residences was performed with a Global Positioning System receiver (GPS Garmin® eTrex 30), and used to perform georeferencing and spatial analysis. The prevalence of CL was 15.49% and it was observed that most cases of the urban area were concentrated in the Frei Damião neighborhood, on the outskirts of the city, where a high-risk cluster for the occurrence of the disease was formed (p = 0.02; RR = 2.48). No statistically significant cluster was observed in rural areas. CL is widely distributed in the municipality of Santa Luzia in a heterogeneous manner and with a tendency to urbanization. The areas identified with high prevalence and highest risk should be prioritized to maximize the efficiency of the Visceral Leishmaniasis Surveillance and Control Program and minimize the chance of new canine and human cases.

show abstract

“…The canine visceral leishmaniasis has already been reported in several municipalities in Paraíba (Silva et al, 2016;Fernandes et al, 2016;Silva et al, 2018). According to the DATASUS, from 2010 to 2018 were notified and confirmed 33 cases of autochthone human visceral leishmaniasis in Sousa-PB, however, this is the first report of feline visceral leishmaniasis in Paraíba.…”

Section: Discussionmentioning

confidence: 88%

Natural Infection by Leishmania infantum in domestic cats (Felis catus) in a municipality of moderate transmission in the Brazilian semi-arid region

Silva

Portela

Arruda

et al. 2020

Rev. Bras. Parasitol. Vet.

Self Cite

View full text Add to dashboard Cite

The main clinical, anatomopathological, and molecular aspects of the infection by Leishmania infantum are described in two cats with multicentric cutaneous, nodular, and ulcerated lesions. The animals were submitted to a clinical examination, followed by serological, molecular and parasitological exams, with culture and isolation of the parasite, and subsequent isoenzymatic characterization. The animals were euthanized and necropsied. Case 1 was an adult, female, mixed-bred stray cat. Case 2 was an adult, male, mixed-bred and domiciled cat. Both were positive for the presence of anti-L. infantum antibodies. In the cytology of the cutaneous nodules and lymph nodes, amastigote forms of Leishmania spp. could be visualized, free and in the interior of the macrophages. In the histopathology, the lesions were characterized by nodular granulomatous and/or ulcerative dermatitis, associated to amastigote forms of Leishmania spp. By means of the polymerase chain reaction, the sequence of the L. infantum kDNA minicircle was amplified. It is concluded that the infection by L. infantum occurs in cats in the State of Paraíba, Northeast region of Brazil and the need to understand the immunological profile of the visceral leishmaniasis in the feline population is highlighted with aimed at the control measures in public health.

show abstract

Seroprevalence and risk factors associated with canine visceral leishmaniasis in the State of Paraíba, Brazil

Cited by 12 publications

References 13 publications

Twice upon a time: The progression of canine visceral leishmaniasis in an Argentinean city

Twice upon a time: The progression of canine visceral leishmaniasis in an Argentinean city

Spatial analysis of canine leishmaniasis in an area of transmission of the semi-arid region of the State of Paraíba, Brazil

Natural Infection by Leishmania infantum in domestic cats (Felis catus) in a municipality of moderate transmission in the Brazilian semi-arid region

Contact Info

Product

Resources

About