Seropositivity for Chagas disease in blood donors from the state of Alagoas, Northeastern Brazil: an 11-year time series study

Abstract

INTRODUCTION Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression model. RESULTS Seropositivity rate during the study period was 0.35%, which decreased from 2014 to 2020, (annual percentage change, APC = -29.38; p- value <0.05), while the total number of tests performed remained stable (APC = 6.5). CONCLUSIONS Despite the drop in the seropositivity for Chagas infection in donors, it is imperative to maintain the screening of donors for the epidemiological control.

Doença de Chagas aguda: Um recorte epidemiológico entre 2012-2021 do estado do Piauí no Brasil

“…No Brasil, a alteração do quadro epidemiológico da DC, em decorrência do fluxo de indivíduos de baixa condição socioeconômica das áreas rurais para urbanas, determinou intensas campanhas de combate ao inseto transmissor, direcionadas pelas ações de controle vetorial, cobertura de sorologia pré-transfusional e outras estratégias de vigilância (Cardoso et al, 2018;Abreu, Bezerra-Santos & Damasceno, 2021;Branquinha et al, 2023).…”