Chronic kidney disease related to renal tuberculosis: a case report

Abstract

Genitourinary tuberculosis (TB) is the third most common form of extrapulmonary TB. A 34-year-old man with severe kidney function loss secondary to renal TB initially presented with urinary symptoms, including dysuria and polacyuria. The diagnosis was based on clinical history and laboratory tests; the urinalysis revealed acid-fast bacilli. The patient's condition stabilized after beginning TB-specific treatment, but the right kidney function loss persisted. Renal TB can lead to irreversible loss of renal function. As such, renal function should be considered in all patients from TB-endemic areas who present with urinary symptoms and whose urine cultures are negative for common pathogens.

An outbreak of tuberculosis due toMycobacterium bovisinfection in a pack of English Foxhounds (2016-2017)

“…TB is usually considered a chronic disease with only a small percentage of infected individuals becoming clinically unwell (Eisenhut, ). Therefore, this rapid progression to disease in a relatively high proportion of animals can be considered unusual, although not unheard of, as sporadic fulminant human cases of renal TB leading to death by acute renal impairment have been reported (Adzic‐Vukicevic et al., ; Dissanayake, ; Isao et al., ; Pathan et al., ; Punia & Kumar, ; da Silva Junior, Brito, Rabelo, & Saboia, ).…”

“…Unusually for companion animals, every clinically ill animal, those with lesions at PME as well as NVL hounds that were found to be culture positive, had renal infections. The kidney is not generally considered a so‐called “target organ” for mycobacterial infections in companion animals, however, it is the second most common site of extra‐pulmonary TB in humans, after lymph nodes (Adzic‐Vukicevic et al., ; Murray et al., ; O'Halloran & Gunn‐Moore, ; Pesciaroli et al., ; da Silva Junior et al., ). Renal tuberculous infections are often considered to be insidious and present with mild or even subclinical disease, a significant proportion of cases are incidental findings at PME (Guarino, Martínez‐Roig, Maiques‐Llacer, González‐Rivero, & Anguerri‐Feu, 2009; Isao et al., ; Punia & Kumar, ).…”