Post-exposure human rabies prophylaxis: spatial patterns of inadequate procedures in Ceará - Brazil, 2007 to 2015

Cavalcante, Kellyn Kessiene de Sousa; Florêncio, Caroline Mary Gurgel Dias; Moreno, Jarier de Oliveira; Correia, Francisco Gustavo Silveira; Alencar, Carlos Henrique

doi:10.1590/0037-8682-0247-2019

Cited by 4 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, PEP knowledge was not higher in more experienced professionals, in contrast to more experienced workers having more awareness of practices to control rabies in India (12). Most health professionals (97%) in our study were unable to correctly classify wounds as "severe" or "light" according to Ministry of Health guidelines, which also strongly influences PEP outcome in Brazil and other countries (27,30). Therefore, our study suggests that more frequent training should help increase PEP knowledge and reduce its misuse.…”

Section: Discussioncontrasting

confidence: 65%

“…Reducing data entry errors or inconsistency and ensuring form completion are key to using SINAN in local and national surveillance for rabies (8). However, many SINAN records include major errors (e.g., rabies false positives) or missing data (8,30). Errors in the SINAN data could arise from the relatively limited amount of time (<20 min for most professionals) to complete the form, the large number of fields (e.g., 60), errors when digiting paper forms, and a lack of feedback about errors (e.g., false positives) detected.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Factors Limiting the Appropriate Use of Rabies Post-exposure Prophylaxis by Health Professionals in Brazil

et al. 2022

View full text Add to dashboard Cite

Post-exposure prophylaxis (PEP) is necessary to prevent the fatal onset of rabies but requires optimization to avoid overuse in populations at risk of rabies. In Brazil, the incidence of dog bites remains high, with almost half of dog-bite patients not receiving the PEP recommended by the Ministry of Health guidelines between 2008 and 2017. In this study, we aimed to identify the factors that limit the appropriate prescribing of PEP by interviewing health professionals responsible for PEP administration and completion of the ‘Information System on Diseases of Compulsory Declaration’ (SINAN) form reporting human anti-rabies care for patients seeking health care after a dog bite. We conducted 147 questionnaires (45 questions each) in three Brazilian states (i.e., Rio Grande do Sul, Santa Catarina, Rio Grande do Norte) including questions related to the criteria used by professionals to classify a dog as “suspect” or “rabid”, knowledge on PEP prescription guidelines, SINAN and communication with veterinarians. Our analyses showed that most health professionals delivering PEP in these three states struggle to identify a rabies “suspect” dog according to the Ministry of Health guidelines, and to indicate the adequate PEP regimen, with only 11% of professionals prescribing the appropriate PEP under various dog-bite patient scenarios. PEP knowledge score was higher among professionals trained on PEP guidelines and working in facilities with the highest incidence of dog bites. In contrast, PEP knowledge scores did not vary significantly between states, and were not correlated to the professional's level of experience, the number of colleagues available at the health unit or the professional's confidence on prescribing appropriate PEP. Our results suggest that knowledge gaps in PEP administration among health professionals of Brazil can be reduced by implementing training programs to differentiate among rabies risk scenarios, prescribe the corresponding appropriate PEP and improve communication between health and veterinary authorities.

show abstract

Section: Discussioncontrasting

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Factors Limiting the Appropriate Use of Rabies Post-exposure Prophylaxis by Health Professionals in Brazil

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Ellipsoids for bat rabies spatial density in Chile demonstrated a particularly strong relationship with metropolitan regions (Escobar et al, 2015). The geographic heterogeneity of rabies cases in the state of Ceará, Brazil are shown in Figure 2, which illustrates the four spatial patterns HH, LL, HL and LH (Cavalcante et al, 2019).…”

Section: Articlementioning

confidence: 93%

Spatial and temporal dynamic analysis of rabies: A review of current methodologies

Chen

2022

Geospat Health

View full text Add to dashboard Cite

Rabies continues to be one of the deadliest, high risk diseases worldwide, posing a severe threat to public health. The lack of human-to-human transmission means that the spread of rabies is not significantly affected by the distribution of humans or migra- tion. Thus, the spatiotemporal dynamic of cases in both wild and domestic animals is an important issue that can result in human cases. This paper gives an overview of the methodologies for the spatial and temporal dynamic analysis of this disease. It introduces the most representative research progress of spatial aggregation, dynamic transmission, spatiotemporal distribution, epidemiologi- cal analysis and application of modelling in the study of rabies transmission in recent years. This overview should be useful for investigating the spatial and temporal dynamics of rabies, as it could help understanding the spread of cases as well as contribute to the development of better prevention and control strategies in ecology and epidemiology.

show abstract

“…The risk of vaccine and anti-rabies serum stock shortage for rabies control is a threat to the successful programs for the control and elimination of dog-maintained rabies in Brazil considering the pre- and post-exposure prophylaxis [ 19 ]. Not only availability, but also high rates of inadequate post-exposure rabies procedures in some Brazilian states should be a concern for health authorities [ 20 ].…”

Section: Challenges For Brazilian Health Surveillancementioning

confidence: 99%

From dogs to bats: Concerns regarding vampire bat-borne rabies in Brazil

et al. 2022

View full text Add to dashboard Cite

Post-exposure human rabies prophylaxis: spatial patterns of inadequate procedures in Ceará - Brazil, 2007 to 2015

Cited by 4 publications

References 9 publications

Factors Limiting the Appropriate Use of Rabies Post-exposure Prophylaxis by Health Professionals in Brazil

Factors Limiting the Appropriate Use of Rabies Post-exposure Prophylaxis by Health Professionals in Brazil

Spatial and temporal dynamic analysis of rabies: A review of current methodologies

From dogs to bats: Concerns regarding vampire bat-borne rabies in Brazil

Contact Info

Product

Resources

About