Authors' reply: Emergence of antibiotic-resistant bacterial strains, methicillin-resistant Staphylococcus aureus and extended spectrum β-lactamases, and multi-drug resistance are problems similar to global warming

Spread of Multidrug-resistant microrganisms: a global threat and critical healthcare problem

“…1 Approximately 40% of hospitalized patients receive antibiotics, however, in about 50% of the cases, the use of antimicrobials is unnecessary. 3 Empirical therapy, paticularly in critical units, is used with a combination of several broad-spectrum antibiotics, allowing multidrug-resistant strains such as Methicillin-resistant Staphylococcus aureus (MRSA), Gram-negative non-fermentative bacteria and Enterobacteriacae family particularly those producing metallo-ß-lactamase and extended spectrum ß-lactamase to emerge and spread quickly.…”