Histopathological findings of nucleus pulposus in lumbar brucellar spondylodiscitis

Abstract

FIGURE 1: Hematoxylin and eosin staining showed that the extracellular matrix had decreased, while collagen fibrils had begun to grow and become more irregularly arranged among the matrix (×200 and ×400). FIGURE 2: Acid-fast staining showed no positive acid-fast bacillus (a1 and a2, ×200 and ×400); periodic acid-Schiff staining showed no positive fungi (b1, b2, ×200 and ×400); gomori methenamine silver staining showed no positive fungi (c1 and c2, ×200 and ×400); and Gram staining showed no positive bacteria (d1 and d2, ×200 and ×400).

Preclinical Models of Brucellar Spondylodiscitis

“…During the past decades, significant progresses to diagnose and treat the Brucellar spondylodiscitis have been achieved [66][67][68][69]. However, many obstacles still exist to be overcome in order to employ and utilize new strategies to refine early detection, diagnosis, therapy [70,71].…”