Chronic mucocutaneous candidiasis associated with paracoccidioidomycosis in a patient with mannose receptor deficiency: First case reported in the literature

Vasconcelos, Dewton de Moraes; Bertolini, Dalton Luis; Ferreira, Maurício Domingues

doi:10.1590/0037-8682-0008-2021

Cited by 3 publications

(1 citation statement)

References 14 publications

(16 reference statements)

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“… None 30 2023 mannose receptor female 1.5 years old >10Y (28Y) Candida spp. Hepatomegaly; polyadenopathy; 31 2021 TRAF3IP2 male 1 years old >10Y (17Y) Candida spp. Hypergammaglobulinemia; bronchiectasis 32 2021 TRAF3IP2 male 6 months >10Y (12Y) Candida spp.…”

Section: Discussionmentioning

confidence: 99%

Chinese Chronic Mucocutaneous Candidiasis: A Case Report Series

Qian,

Zhang,

Shi

et al. 2024

IDR

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Chronic Mucocutaneous Candidiasis (CMC) is a rare immunodeficiency disease characterized by chronic or recurrent superficial Candida infections on the skin, nail, and mucous membranes. Here, we present four Chinese patients with CMC who manifested oral mucosal leukoplakia and nail thickening during early childhood, all displaying fissured tongue lines. The causative pathogens isolated from their oral mucosa and nails were identified as C. albicans and C. parapsilosis through morphology and molecular sequencing. Notably, among the four patients, one presented with vitiligo, while another had hypothyroidism. We have also conducted a review of reported cases of CMC in China and worldwide over the last five years, highlighting potential approaches for diagnosis and treatment. The current molecular evidence in the literature suggests potential for the development of early diagnosis methods, such as screening genetic variables on STAT1 and STAT3 . Additionally, potential treatment avenues, including gene-targeted analogues and GM-CSF analogues, could be explored in conjunction with traditional antifungal therapy.

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Section: Discussionmentioning

confidence: 99%

Chinese Chronic Mucocutaneous Candidiasis: A Case Report Series

Qian,

Zhang,

Shi

et al. 2024

IDR

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The mannose receptor ligands and the macrophage glycome

Cummings

2022

Current Opinion in Structural Biology

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Chronic mucocutaneous candidiasis: case report

Peláez Yáñez,

Orraca Castillo,

García García

et al. 2024

Salud, Ciencia y Tecnología

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Chronic mucocutaneous candidiasis is characterized by infections caused by Candida sp, usually Candida albicans, which may be persistent or recurrent on skin, mucous membranes and nails; generally confined on the cutaneous surface and occasionally systemic dissemination. This can be associated to endocrinopathies and autoimmunity. We report a case of chronic mucocutaneous candidiasis with liver disease secondary to treatments with fluconazole, with positive response to topical treatments of itraconazole and others, as well as immunostimulation.

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Chronic mucocutaneous candidiasis associated with paracoccidioidomycosis in a patient with mannose receptor deficiency: First case reported in the literature

Cited by 3 publications

References 14 publications

Chinese Chronic Mucocutaneous Candidiasis: A Case Report Series

Chinese Chronic Mucocutaneous Candidiasis: A Case Report Series

The mannose receptor ligands and the macrophage glycome

Chronic mucocutaneous candidiasis: case report

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