Breast cancer screening program for risk groups: facts and perspectives

Abstract

Objectives: to measure the frequency and compliance of breast cancer screening, according to the risk for this disease. Methods: a cross-sectional study with 950 female users of 38 public Primary Health Care services in São Paulo, between October and December 2013. According to UHS criteria, participants were grouped into high risk and standard risk, and frequency, association (p≤0.05), and screening compliance were measured. Results: 6.7% had high risk and 93.3% standard risk, respectively; in these groups, the frequency and compliance of clinical breast examination were 40.3% and 37.1%, and 43.5% and 43.0% (frequency p=0.631, compliance p=0.290). Mammograms were 67.7% and 35.5% for participants at high risk, and 57.4% and 25.4% for those at standard risk (frequency p=0.090, compliance p=0.000). Conclusions: in the groups, attendance and conformity of the clinical breast exam were similar; for mammography, it was higher in those at high risk, with assertiveness lower than the 70% set in UHS.

Dicer-mediated miR-200b expression contributes to cell migratory/invasive abilities and cancer stem cells properties of breast cancer cells

“…Breast cancer is one of the most common malignant neoplasms in women and remains a leading cause of morbidity worldwide [ 1 ]. In the United States, the prevalence of breast cancer is one per eight individuals, and a woman is diagnosed as having breast cancer every 2 min [ 2 , 3 ]. Although breast cancer treatment has considerably advanced over the years and patient survival has improved, 20 percent to 30 percent of breast cancer patients still develop distant metastases within two years [ 4 ].…”