Biological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida

Vieira, Daniglayse Santos; Oliveira, Fabianny Torres de; Suárez, Jorge Andrés García; Silva, Davi Porfirio da; Bernardo, Thaís Honório Lins; Bastos, Maria Lysete de Assis

doi:10.1590/0034-7167-2020-0451

Cited by 8 publications

(3 citation statements)

References 29 publications

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“…Other species of the genus Jatropha was J. gossypiifolia and J. multifidi, which were used for wound healing. The importance of Jatropha was also reported to have biological benefits such as anti-microbial, anti-infectious and healing properties by other study reports (Xavier-Santos et al 2018;Vieira et al 2021).…”

Section: Discussionmentioning

confidence: 89%

Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia

HUSAINI

MAULANY²,

NASRI³

et al. 2022

Biodiversitas

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Abstract. Husaini IPA, Maulany RI, Nasri N, Ngakan PO. 2022. Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia. Biodiversitas 23: 5539-5550. The people of Minasatene (Pangkep District) in Bantimurung-Bulusaraung National Park, South Sulawesi (Indonesia) have used traditional medicinal plants for many centuries. However, this local knowledge has not been recorded. This study aims to examine the diversity of plant species used to treat various ailments in the area. A set of semi-structured questionnaires was distributed to 60 respondents, consisting of traditional healers, elderly people, herb sellers and local people of Minasatene. This was used to obtain a demographic profile, vernacular names of plants and their uses, plant parts used, modes of preparation and methods of application. The diversity and use of the medicinal plant species in a traditional context were descriptively analyzed. The data were further extrapolated using Use Value (UV) to analyze the relative importance of plant species based on the number of uses; Fidelity Level (FL) to determine the specific uses of each plant species and preference over other species, and Informant Consensus Factor (ICF) to investigate an agreement between each group of diseases and related remedies. The study reveals that there were 74 species of medicinal plants belonging to 65 genera and 44 families being used as traditional medicines, which have been known to treat 54 ailments. Among the plant species, soursop (Annona muricata) had the highest UV (0,95), while the fig tree species, Ficus septica (100%) had the highest FL with the most frequent citation. From the data gained, it was found that skeletomuscular disorders had the highest ICF value (0,92).

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Section: Discussionmentioning

confidence: 89%

Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia

HUSAINI

MAULANY²,

NASRI³

et al. 2022

Biodiversitas

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“…27 The content of terpenoids (multidione, multifidone, multifolone, multifidanol, and multifidenol) is useful due to its anticancer, antitumor, antileshmanial, antimalarial, antimicrobial, cytotoxic, insecticide, and molluscidal activities, which have been described previously. 28,29 The binding affinity describes the strength/affinity of the bond resulting from the receptor-ligand interaction in the form of low energy in the formation of the receptor drug complex. This indicates the stability of the interaction (binding) of the ligand with the receptor at the binding site.…”

Section: Discussionmentioning

confidence: 99%

The potential active compounds of Jatropha multifida Linn. as an anti-COVID-19 mouthwash: In silico study

Effendi,

'Ayun,

Putri

et al. 2024

Dent. J.

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Background: Povidone-iodine 1% mouthwash is one of the products recommended for preventing and controlling COVID-19 infection in dental procedures. Jatropha multifida Linn. has the same antiseptic effect as povidone-iodine. Purpose: The objective is to determine the effectiveness and interaction effect of secondary metabolites from the latex of Jatropha multifida Linn. and povidone-iodine against the main protease (MPro) SARS-CoV-2 and the SARS-CoV-2 spike protein - ACE2 receptors. Methods: The in silico test was used in this study and carried out using the Molegro Virtual Docker software for molecular docking and BIOVIA Discovery Studio and PyMOL for visualization. Results: The results show that secondary metabolite compounds contained in the latex of Jatropha multifida Linn. have a better effectiveness potential in relation to MPro SARS-CoV-2 and SARS-CoV-2 spike protein - ACE2 receptors than povidone-iodine. Conclusion: The latex of Jatropha multifida Linn. shows potential as a preventive and curative therapy for COVID-19 in the in silico study.

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“…Penggunaan antioksidan dapat menetralkan atau melawan bahan toksik serta mengurangi terjadinya kerusakan sel pada tubuh yang diakibatkan proses oksidasi radikal bebas (Vieira et al, 2021). Saat ini masyarakat tertarik dengan penggunaaan antioksidan alami, salah satu antioksidan alami yang memiliki kemampuan penangkapan radikal pada elektrofilik dan active oxygen species adalah golongan fenolik (He et al, 2009).…”

Section: Pendahuluanunclassified

Uji aktivitas antioksidan dan sitotoksik ekstrak daun Jarak Pagar (Jatropha curcas)

Rahman

Toepak

Angga

et al. 2023

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Background: antioxidants play an important role in preventing cell damage and generating inhibition of signalling pathways of cancer, aging and various diseases. Several extracts, oils, and herbal formulations were shown to be important Antioxidant agents for preventing cell damage. Jarak Pagar (Jatropha Curcas) leaves. were a common natural Antioxidant phytochemical screening of Jatropha leaves that contained flavonoids, where flavonoids acted as antioxidants.Objectives: this study aims to determine the Antioxidant and cytotoxic activity of ethanol extract of Jatropha leaves using the DPPH and shrimp larvae method, respectively.Methods: the design in this study was quasi-experimental, using various concentrations of ethanol extract and vitamin C (comparison control) in inhibiting free radicals and each Concentration was repeated three repetitions. The research was conducted at the Laboratory of Chemistry FMIPA Palangka Raya University and Chemistry Education FKIP Halu Oleo University in 2022. The ethanol extract of Jatropha leaves weighing 60 grams was extracted using the Soxhletion method to obtain 1.667 grams of thick ethanol extract. Phytochemical characterization was further conducted by tube method, Antioxidant tests by DPPH (1,1-diphenyl-2-picrylhydrazyl) and cytotoxic test assessed by the Brine Shrimp Lethality Test (BSLT) method. The data analysis used the One Way Anova statistical test and continued with post hoc Tamhane at 95% Cl.Results: the results showed that Jatropha curcas L. leaves contained several secondary metabolites such as flavonoids, saponins, alkaloids, polyphenols and tannins. Furthermore, the Antioxidant activity test of ethanol extract of Jatropha curcas L leaves and control (vitamin C) provided IC50 of 32.83 ± 0.09 (μg/mL) and 8.78 ± 0.21 (μg/mL), respectively. Another finding found that ethanol extract of Jatropha leaves contained active compounds that were toxic to shrimp larvae with LC50 of 427 ppm. Based on the One Way Anova test, each Concentration had a significant difference in the percentage of radical scavenging (p= 0,05). The Concentration of 160 ppm is the most effective in radical scavenging.Conclusion: we concluded that the ethanol extract of Jatropha leaves showed strong Antioxidant activity and potential as an anticancer agent

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Biological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida

Cited by 8 publications

References 29 publications

Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia

Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia

The potential active compounds of Jatropha multifida Linn. as an anti-COVID-19 mouthwash: In silico study

Uji aktivitas antioksidan dan sitotoksik ekstrak daun Jarak Pagar (Jatropha curcas)

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