Infection related to Klebsiella pneumoniae producing carbapenemase in renal transplant patients

Abstract

Objective: To evaluate the risk factors related to Klebsiella pneumoniae carbapenemase infection after renal transplantation. Methods: This was a retrospective epidemiological (case-control) study, conducted from October 2011 to march 2016. Transplanted patients with infection by this bacteria during hospitalization were selected as cases. The controls were paired by age, sex, type of donor and transplant time. The proportion of cases and controls was 1:2. Results: Thirty hundred and five patients were included in the study (45 cases and 90 controls). The risk factors found for infection by KPC were: time of hospitalization after the transplant (OR: 4.82; CI95% 2.46-9.44), delayed kidney function (OR: 5.60; CI95% 1.91-11.01) and previous infectious for another microorganism ( OR: 34.13 CI95% 3.52-132.00). Conclusion: The risk of acquisition of this bacterium was directly related to invasive procedures and exposure to the hospital environment. The findings reinforce the importance of prevention measures and control of infection by this microorganism.

Analysis of Risk Factors for Carbapenem-Resistant Klebsiella pneumoniae Infection and Its Effect on the Outcome of Early Infection After Kidney Transplantation

“…Other studies have also predicted risk factors for CRKP infections, such as DGF, diabetes (Varotti et al, 2017;Taminato et al, 2019;Vigara et al, 2020). In our analysis, these factors were not associated with a higher risk of CRKP infection.…”

Nursing care of the chronic renal patient on hemodialysis using double lumen catheter / Cuidados de enfermagem ao paciente renal crônico em hemodiálise em uso de cateter duplo lúmen

“…The literature reports that the nurse is usually responsible for the care related to the dressing of the double lumen catheter 7 , with the scenario reported here being unusual. It is believed that this is related to the reduced number of nurses in the team.…”

Prevention and Treatment of Carbapenem-Resistant Organism Bacilli from Liver Transplantation Donors – Single Center Experience

“…For donors, there is often a history of ICU admission, major surgery, tracheostomy and mechanical ventilation, intubation of deep venous, the indwelling of urinary catheters, prolonged bed rest, and use of broad-spectrum antibiotics, making them vulnerable to various infections, especially drug-resistant bacterial infections. 10 The distribution of infectious agents varies depending on the endemic region. In this study, a total of 267 pathogenic strains were detected in 120 donor-related specimens and organ preservation solutions, with 105 drug-resistant strains and a 39.32% detection rate of drug-resistant bacteria.…”