Migrainous periorbital ecchymosis

Reply to: post‐emesis periorbital purpura in hyperemesis gravidarum

“…access journals, up from 741 in the year 2000. 2 The percentage of open access papers of all publications rose from 9.5 to 24% from 1998 to 2018. 3 Despite this explosive growth, many signature journals remain primarily subscription based or they have adopted a hybrid model in which authors can pay for open access.…”

“…Another neurological cause of periorbital ecchymosis, aside from the already described cerebral venous thrombosis, is a migraine attack. It can reflect complex neurovascular changes, specifically vasodilation of intracranial and extracerebral blood vessels through the release of vasoactive substances 2 …”

“…It can reflect complex neurovascular changes, specifically vasodilation of intracranial and extracerebral blood vessels through the release of vasoactive substances. 2 There have been reports of iatrogenic periorbital ecchymosis related to endoscopic techniques 3 and to continuous positive airway pressure therapy. 4 Postexercise purpura usually occurs after prolonged weight-bearing activity on the legs, and the severity of the lesions depends on exercise intensity and high ambient temperature.…”

“…There is now "The Directory of Open Access Journals" webpage that lists open access journals that meet certain quality metrics. 2 With a trend toward open access, we must proceed with caution. Open access has increased the speed and breadth of publishing and made new discoveries freely available to all.…”