Gliosarcomas: magnetic resonance imaging findings

Fukuda, Aya; Queiróz, Luciano de Souza; Reis, Fabiano

doi:10.1590/0004-282x20190158

Cited by 8 publications

(5 citation statements)

References 47 publications

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“…The edema around the mass exhibited no enhancement, and the invaded adjacent meninges exhibited clear linear enhancement. 23 , 25 In this study, all 14 patients underwent non-enhanced MRI scanning and enhanced MRI scanning, and the morphological changes, signal characteristics, and edema of the masses were consistent with those reported in the literature. Seven cases exhibited irregular annular enhancement and enhancement in the cystic wall of giant cystic degeneration, seven cases had clear mass enhancement, and two cases had clear enhancement of the invaded meninges.…”

Section: Discussionsupporting

confidence: 84%

Computed Tomography, Magnetic Resonance Imaging, and Pathological Features of Gliosarcoma

Fan¹,

Yu²,

Du³

et al. 2022

NDT

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To investigate the clinical, imaging, and pathological features of gliosarcoma. Methods: The clinical data of 14 patients with gliosarcoma confirmed by surgery and pathology at our hospital between 2010 and 2021 were analyzed retrospectively, and the relevant literature was reviewed.Results: In all 14 cases, the gliosarcoma was located in the supratentorial brain parenchyma and involved a single lesion. There were more male patients (64.3%) than female patients (35.7%), and 57.1% of all the patients were 40-60 years of age. The prognosis of all 14 patients was poor, and the average survival time was approximately seven months. The computed tomography findings revealed mostly mixed density lesions, and some cases were complicated with bleeding. The magnetic resonance imaging revealed irregularly shaped mass lesions of different sizes, with uneven or circular enhancement. Cystic degeneration and necrosis could be seen in all the masses, some of which showed signs of bleeding and were surrounded by different degrees of edema and space-occupying effects. The pathological examination revealed that the tumors had bidirectional differentiation of the glial and sarcoma components, while the immunohistochemistry examination revealed glial fibrillary acidic protein-positive and reticular fiber-positive staining in the sarcoma. Conclusion:The clinical manifestations of gliosarcoma are nonspecific, but imaging reveals that the condition has certain characteristics, typically consisting of a huge supratentorial mass, with an irregular heterogeneous periphery or obvious mass-like augmentation after enhancement. The final diagnosis depends on the results of a pathological examination.

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Section: Discussionsupporting

confidence: 84%

Computed Tomography, Magnetic Resonance Imaging, and Pathological Features of Gliosarcoma

Fan¹,

Yu²,

Du³

et al. 2022

NDT

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“…Three patients described by Fukuda et al. presented with increased relative cerebral blood volume in the tumor compared with the surrounding normal white matter [18] . DTI is a non-invasive technique based on the principle of anisotropic water molecule diffusion in axons.…”

Section: Discussionmentioning

confidence: 95%

Primary intraventricular gliosarcoma on MRI: A challenging diagnosis

Tuan

Hung

Minh

et al. 2022

Radiology Case Reports

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Gliosarcoma (GS) is an uncommon central nervous system tumor with several characteristics of a malignant neoplasm and poor prognosis. The majority of GS reports describe a predilection for the cerebral hemispheres, and cases of intraventricular GS are extremely rare, with only a few reported. In addition, intraventricular GS has not been associated with any unique radiographic or clinical features, which can result in misdiagnosis as other intraventricular tumor types. In this report, we present the case of a 32-year-old woman with GS in the trigone of the lateral ventricle and provide a retrospective review of similar, previously reported cases.

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“…A gliosarcoma is a rare biphasic glial and sarcomatous variant of GBM with similar prognosis following standard treatment [14]. Of note, gliosarcoma is indistinguishable from GBM when the diagnosis is only based on clinical and neuroimaging characteristics [15]. Pathological diagnoses of all included grade 4 astrocytic tumors (GBM, gliosarcoma) were based on the wellestablished criteria set out in the contemporary fourth edition of the World Health Organization classification of tumors of the central nervous system [16].…”

Section: Patients and Proceduresmentioning

confidence: 99%

Determining the applicability of the RSNA radiology lexicon (RadLex) in high-grade glioma MRI reporting—a preliminary study on 20 consecutive cases with newly diagnosed glioblastoma

et al. 2022

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Background The implementation of a collective terminology in radiological reporting such as the RSNA radiological lexicon (RadLex) yields many benefits including unambiguous communication of findings, improved education, and fostering data mining for research purposes. While some fields in general radiology have already been evaluated so far, this is the first exploratory approach to assess the applicability of the RadLex terminology to glioblastoma (GBM) MRI reporting. Methods Preoperative brain MRI reports of 20 consecutive patients with newly diagnosed GBM (mean age 68.4 ± 10.8 years; 12 males) between January and October 2010 were retrospectively identified. All terms related to the tumor as well as their frequencies of mention were extracted from the MRI reports by two independent neuroradiologists. Every item was subsequently analyzed with respect to an equivalent RadLex representation and classified into one of four groups as follows: 1. verbatim RadLex entity, 2. synonymous/multiple equivalent(s), 3. combination of RadLex concepts, or 4. no RadLex equivalent. Additionally, verbatim entities were categorized using the hierarchical RadLex Tree Browser. Results A total of 160 radiological terms were gathered. 123/160 (76.9%) items showed literal RadLex equivalents, 9/160 (5.6%) items had synonymous (non-verbatim) or multiple counterparts, 21/160 (13.1%) items were represented by means of a combination of concepts, and 7/160 (4.4%) entities could not eventually be transferred adequately into the RadLex ontology. Conclusions Our results suggest a sufficient term coverage of the RadLex terminology for GBM MRI reporting. If applied extensively, it may improve communication of radiological findings and facilitate data mining for large-scale research purposes.

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Gliosarcomas: magnetic resonance imaging findings

Cited by 8 publications

References 47 publications

Computed Tomography, Magnetic Resonance Imaging, and Pathological Features of Gliosarcoma

Computed Tomography, Magnetic Resonance Imaging, and Pathological Features of Gliosarcoma

Primary intraventricular gliosarcoma on MRI: A challenging diagnosis

Determining the applicability of the RSNA radiology lexicon (RadLex) in high-grade glioma MRI reporting—a preliminary study on 20 consecutive cases with newly diagnosed glioblastoma

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