Prevalence of multiple sclerosis in Goiânia, Goiás, Brazil

Ribeiro, T.A.G.J.; Duarte, Aline Leite; Silva, Delson José da; Borges, Fernando Elias; Costa, Vanessa Maia da; Alvarenga, Regina Maria Papais; Diniz, Denise Sisterolli

doi:10.1590/0004-282x20190032

Cited by 9 publications

(14 citation statements)

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“…Although the degree of disability was moderate, we observed a high number of patients with an EDSS value greater than 5.0, which can be explained by the fact that many patients had been diagnosed several years before. Most Brazilian cohorts reported EDSS values below 4.0 3,19 , similar to values reported in other international studies 6,17,20 .…”

Section: Discussionsupporting

confidence: 87%

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Association of clinical epidemiological factors to polypharmacy among patients with multiple sclerosis: real-life data

et al. 2021

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Introduction: Treatment for multiple sclerosis should focus on relapse prevention and treatment, as well as symptom and disease progression control, which require the use of multiple medications. Objective: To evaluate the association of polypharmacy and related clinical, epidemiological factors in multiple sclerosis patient cohorts. Methods: It was conducted a prospective study of multiple sclerosis patients that held a prescription of disease-modifying drugs between January and December 2017. The medications were analyzed and classified as either long-term or as-needed medications for therapeutic objective and prescription status purposes. Results: During 2017, 124 patients were attended, 106 were eligible for the study, and 81 agreed to participate. The average age was 40.95±11.69 years. The disease duration varied between 6 months and 30 years, with a median of 7 years. More than half of the multiple sclerosis patients suffered from comorbidities (54.32%), and 76.54% were categorized as polypharmacy. The comparison of polypharmacy between the groups yielded significant differences for comorbidities and employment status and regarding age between patients with polypharmacy and patients without polypharmacy of long-term medications. Conclusion: The age of the patient and the presence of comorbidities are important factors related to polypharmacy.

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Section: Discussionsupporting

confidence: 87%

“…This prevalence varies considerably between countries 2 . In Brazil, it is estimated that the prevalence of MS ranges from 0.75 to 30.7 cases per 100,000 inhabitants, depending on the characteristics of the population studies performed 3 .…”

Section: Introductionmentioning

confidence: 99%

Association of clinical epidemiological factors to polypharmacy among patients with multiple sclerosis: real-life data

et al. 2021

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“…The prevalence and incidence of MS is increasing globally, including in parts of Eastern and Southern Europe [11][12][13], Asia [14,15] and Latin America [16,17]. This global reach means that advice and guidelines around standards of patient-centred care will increasingly need to account for a greater diversity of cultural backgrounds and family structures and dynamics than might previously have been the case.…”

Section: Discussionmentioning

confidence: 99%

“…While shared decision-making has historically been viewed as a partnership solely between PwMS and HCPs, certain situations may also require the involvement of family members. This involvement may be driven by a personal or cultural preference of the PwMS; the cultural aspects of family involvement require further research, given that although MS is relatively well studied in North America and parts of Europe, it is generally not so well studied in other regions where the prevalence and incidence of MS are increasing, including in parts of Eastern and Southern Europe [11][12][13], Asia [14,15] and Latin America [16,17]. In addition, more recently, a more direct decision-making need may exist in cases of pregnancy and family planning [18], which have become more important elements to consider with the large improvement in MS care and understanding of MS in pregnancy in recent years.…”

Section: Introductionmentioning

confidence: 99%

Caregiver Involvement in MS: Duty or Disruption?

et al. 2021

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Multiple sclerosis (MS) is a complex condition with numerous physical, cognitive and emotional symptoms. These may necessitate significant, permanent lifestyle changes for people with multiple sclerosis (PwMS) and their caregivers and families, meaning it is important in contemporary neurological practice to consider including families and/or caregivers in the management of MS. However, existing evidence suggests that family involvement is not always beneficial; for example, it can exert either a strong positive or negative influence on the ability of PwMS to achieve optimal outcomes from their treatment and disease management. This paper, based on a live debate between neurologists and PwMS, examines the current perceptions on constructive involvement of families and caregivers in consultations for and management of MS, and reveals several areas where additional studies are warranted. Shared decision-making in MS has historically been a collaboration solely between healthcare professionals (HCPs) and PwMS, but PwMS are now more frequently being accompanied to appointments by a support person. This paper encourages HCPs to understand the dynamics between PwMS and their support person, and to individualize consultations and information accordingly. Family and caregiver involvement in the provision of care for PwMS needs to be for the benefit of, and at the discretion of, the PwMS. Support for families of PwMS, although important, may be more effectively and appropriately delivered through other channels outside of the clinical setting. Educating HCPs on the current patient experience to enable them to provide improved personalized care will ensure a mutualistic, patient-centred relationship with PwMS, which will help to optimize outcomes. Communication tools may also facilitate these interactions.

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“…O número estimado de pessoas com EM no mundo aumentou de 2,1 milhões em 2008 para 2,3 milhões em 2013 (4,5) . As prevalências de EM encontradas em estudos realizados no Brasil variaram de 1,36 / 100.000 habitantes em Recife (região noroeste) a 27,2 / 100.000 habitantes na cidade de Santa Maria, Rio Grande do Sul (região sul) (6) .…”

Section: Introductionunclassified

Associação entre avaliação clínica e autopercepção da deglutição com a escala de incapacidade motora em pacientes com esclerose múltipla

Piloti

Ruiz

Ribeiro

et al. 2022

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RESUMO Objetivo Investigar a associação entre a avaliação clínica e autopercepção da deglutição com a escala de incapacidade motora em pacientes com Esclerose Múltipla. Método Estudo transversal, prospectivo realizado com indivíduos com Esclerose Múltipla atendidos pelo ambulatório de Neuroimunologia de um hospital do sul do Brasil. Realizamos a revisão dos prontuários eletrônicos dos pacientes para extração do escore da última Expanded Disability Status Scale. Após a análise dos critérios de inclusão, e em consulta clínica, foram aplicados dois protocolos, o de autopercepção para o risco de disfagia, através do instrumento de equivalência brasileira do Eating Assessment Tool e a avaliação clínica da deglutição, com alimentos, através da escala Gugging Swallowing Screen. Os dados foram analisados através de tabelas, estatísticas descritivas e pelos testes: Teste de Associação Exato de Fisher e Teste Qui-quadrado para avaliar a associação entre os resultados das escalas aplicadas. Consideramos um nível de significância máximo de 5% (p<0,05). Resultados Foi possível observar que houve associação significativa entre os escores das escalas Gugging Swallowing Screen com a Expanded Disability Status Scale dos pacientes. Além disso, também se observou relação entre os resultados de ambos protocolos com a Expanded Disability Status Scale. Conclusão Os pacientes com Esclerose Múltipla deste estudo apresentaram disfagia orofaríngea. Houve associação entre os achados da avaliação clínica, do instrumento de autopercepção da deglutição e da escala de incapacidade motora em pacientes com esclerose múltipla.

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Prevalence of multiple sclerosis in Goiânia, Goiás, Brazil

Cited by 9 publications

References 14 publications

Association of clinical epidemiological factors to polypharmacy among patients with multiple sclerosis: real-life data

Association of clinical epidemiological factors to polypharmacy among patients with multiple sclerosis: real-life data

Caregiver Involvement in MS: Duty or Disruption?

Associação entre avaliação clínica e autopercepção da deglutição com a escala de incapacidade motora em pacientes com esclerose múltipla

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