Hoarding disorder secondary to pituitary adenoma: a case study

Abstract

Forty-three-year-old female with hoarding disorder for one year. No other neuropsychiatric background was referred. No laboratory changes. MRI showed a solid-cystic expansive tumor of 65 x 47 x 41mm with significant mass effect over adjacent structures. Patient went through neurosurgery but died at the second day of post-operatory. Surgical pathology showed a slow-growth non-secreting pituitary adenoma. Neuroimaging studies of patients with hoarding disorder have drawn attention to specific brain regions related to the symptoms, including anterior cingulate cortex, dorsolateral prefrontal cortex and orbitofrontal cortex 1,2,3 . These structures were compressed by the tumor in the present case and could hypothetically be related to clinical presentation.

Trigeminal nerve stimulation for the treatment of major depressive disorder and obsessive-compulsive disorder: a case study

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Excessive activities in orbitofrontal-striatal regions, medial and lateral frontal areas, such as the supplementary motor area, anterior cingulate, dorsolateral prefrontal cortex and parietal regions (Trevizol et al, 2016b) in the brain are associated with the inability of obsessive-compulsive disorder (OCD) patients to suppress intrusive thoughts, impulses, or images and repetitive motor responses. Neuromodulation techniques have been proposed as add-on strategies for modulating brain areas involved in OCD symptoms (Trevizol et al, 2016e).

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