Marchiafava-Bignami disease in an AIDS patient

The article considers etiopathogenetic, clinical, diagnostic and therapeutic aspects (characteristics) of disease (syndrome) of Marchiafava-Bignami. It is emphasized that this condition in most of the cases is related to chronic alcoholism though it can occur and under other diseases (diabetes mellitus, sepsis, etc.). Despite to previous opinion about inevitable lethality of disease (syndrome) of Marchiafava-Bignami, broad implementation in clinical practice of methods of neurovisualisation and especially NMR technique, demonstrated that this disease can have not so negative prognosis, It is not excluded that in medical clinical practice more light forms of disease (syndrome) of Marchiafava-Bignami are not diagnosed. The differentiated diagnostic is implemented in relation to a number of neurological diseases, including acute disorders of cerebral circulation, lymphoma, multiple sclerosis. The results of NMR of brain play major role in proper diagnostic of disease (syndrome) of Marchiafava-Bignami. The treatment of disease requires vitamins of group B, especially vitamin B1 (thiamine) and corticosteroids. However, estimate of effectiveness of similar treatment requires further investigations.

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The disease (syndrome) of Marchiafava-Bignami

Damulin

Владимирович²,

Strutsenko

et al. 2016

Medical Journal of the Russian Federation

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Marchiafava-Bignami disease in an AIDS patient

Cited by 1 publication

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The disease (syndrome) of Marchiafava-Bignami

The disease (syndrome) of Marchiafava-Bignami

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