2013
DOI: 10.1590/0004-282x20130134
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Is it correct for a woman with multiple sclerosis to forgo medication because she may become pregnant?

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Cited by 4 publications
(3 citation statements)
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References 10 publications
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“…All the published data come from observational reports and may not be considered very robust [ 84 ]. On the other hand, the overly simplistic solution of withdrawing all treatments from women who intend to conceive (or are already pregnant) does not take into consideration the potential severity of MS [ 85 ]. Severe rebounding of MS activity may occur when fingolimod or natalizumab is withdrawn during pregnancy (or at the time of pregnancy planning) [ 86 91 ].…”
Section: The Effect Of Ms Therapy On Childbearingmentioning
confidence: 99%
“…All the published data come from observational reports and may not be considered very robust [ 84 ]. On the other hand, the overly simplistic solution of withdrawing all treatments from women who intend to conceive (or are already pregnant) does not take into consideration the potential severity of MS [ 85 ]. Severe rebounding of MS activity may occur when fingolimod or natalizumab is withdrawn during pregnancy (or at the time of pregnancy planning) [ 86 91 ].…”
Section: The Effect Of Ms Therapy On Childbearingmentioning
confidence: 99%
“…Analysis of a global database of 425 pregnancies exposed to IFN b-1a followed prospectively determined that there was no increased risk of either spontaneous abortions or congenital anomalies [Sandberg-Wollheim et al 2011]. Many practitioners recommend discontinuing IFN prior to attempts at conception, though in certain cases, there are those who argue it may be acceptable to continue IFNs up to conception, or even throughout pregnancy [Coyle et al 2004;Fragoso, 2013;Ghezzi et al 2013].…”
Section: Safetymentioning
confidence: 99%
“…Many practitioners recommend discontinuing IFN prior to attempts at conception, though in certain cases, there are those who argue it may be acceptable to continue IFNs up to conception, or even throughout pregnancy [Coyle et al . 2004; Fragoso, 2013; Ghezzi et al . 2013].…”
Section: Ifn β (Ifn β-1a: Rebif Avonex Plegridy; Ifn β-1b: Betaseromentioning
confidence: 99%