Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease

Fragoso, Yára Dadalti; Adoni, Tarso; Almeida, Sandra Maria Garcia de; Alves-Leon, Soniza Vieira; Arruda, Walter Oleschko; Barbagelata-Aguero, Fiorella; Brooks, Joseph Bruno Bidin; Carrá, Adriana; Claudino, Rinaldo; Comini-Frota, Elizabeth Regina; Correa, Eber Castro; Damasceno, Alfredo; Damasceno, Benito Pereira; Diaz, Ethel Ciampi; Elliff, David George; Fiore, Ana Patricia Peres; Franco, Clélia Maria Ribeiro; Giacomo, Maria Cristina B.; Gomes, Sidney; Gonçalves, Marcus Vinícius Magno; Grzesiuk, Anderson Kuntz; Inojosa, Jose Luiz; Kaimen-Maciel, Damacio Ramón; Lin, Kátia; Lopes, Josiane; Lourenço, Gisele Alexandre; Martínez, Alejandra; Melcon, Mario O.; Morales, Nívea de Macedo Oliveira; Morales, Rogerio Rizo; Moreira, Marcos Aurélio; Moreira, Shirlene Vianna; Oliveira, Celso Luis da Silva; Oliveira, Francisco Tomaz Menezes de; Ribeiro, João Batista; Ribeiro, Sonia Beatriz Felix; Rodríguez, Claudia; Russo, Liliana; Safanelli, Juliana; Shearer, Kirsty; Siquineli, Fabio; Vizcarra, Darwin

doi:10.1590/0004-282x20130098

Cited by 13 publications

(15 citation statements)

References 22 publications

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“…Study of different latitudes of South America showed significant variation. Patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes (12). Regarding the MOB and risk of MS, vitamin D, as a promoter of some alleles, also promotes Th2 function and inhibit the proinflammatory cytokines, IL-1a, IL-2β, and TNFα (13).…”

Section: Introductionmentioning

confidence: 99%

Scattering Month and Day of Baby Delivery in a Retrospective Survey Linked to 1484 Patients With Multiple Sclerosis

Tolou-Ghamari

2015

Arch Neurosci

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Background: Multiple Sclerosis (MS) is an inflammatory demyelinating disease leading to formation of brain lesions that could produce numerous devastating clinical problems. There are controversial reports related to the type of association of MS with the seasons of birth. Objectives: This study aimed to rank and describe the effect of different months and days of birth on MS. Patients and Methods: The study was conducted in Isfahan University of Medical Sciences, Isfahan, Iran. A total of 1484 patients with MS were included: 1111 females and 373 males. Demographic and clinical data were recorded in a database and were analyzed using SPSS. Results: The population of females with MS had surpassed that of males (75% vs. 25%). The mean age of patients was 34.7 years (range from 7 to 88 years) with 85% of population being younger than 50 years old. The season of birth was winter in 21% of patients. There was a decreased risk of MS in those born in February and March. The prevalence of MS increased from April and reached a peak in May and September. Day of birth was associated with the birthday on 19th day of month in 44% of patients. Conclusions: This investigation supports earlier reports of increased and diminished prevalence of MS in those born in the spring and winter months, respectively. Pharmacotherapy using vitamin D might have beneficial effect in Iranian population, especially in females during pregnancy and their newborns. Therefore, further clinical researches focused on prescription of vitamin D, genetic, daily photoperiod, and geo-epidemiologic differences of disease are recommended.

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Section: Introductionmentioning

confidence: 99%

Scattering Month and Day of Baby Delivery in a Retrospective Survey Linked to 1484 Patients With Multiple Sclerosis

Tolou-Ghamari

2015

Arch Neurosci

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“…Multiple sclerosis (MS) is a chronic disease in which patient independence requires training in self-care and self-management [1]. About 2.5 million people around the world [2], and 5-30 individuals per 100,000 people in Iran suffer from MS [3]. The prevalence of the disease is unfortunately on the rise in Iran and the number of MS cases recorded in different medical centers of the country have increased by three-four times over the past several years [4].…”

Section: Introductionmentioning

confidence: 99%

Effects of Pelvic Floor Muscle Exercises on Urinary Incontinence and Quality of Life in Patients with Multiple Sclerosis

Rafii¹,

Sajjadi²,

Shareinia³

2018

ME-JFM

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“…There are about 2.5 million people with MS worldwide (2). The prevalence of MS is reported as 5 -30 per 100,000 people in Iran (3).…”

Section: Introductionmentioning

confidence: 99%

Pelvic Floor Muscle Training Instruction to Control Urinary Incontinence and its Resulting Stress, Anxiety and Depression in Patients with Multiple Sclerosis

Rafii

Sajjadi

Shareinia

et al. 2016

Jundishapur J Chronic Dis Care

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Background: Urinary disorders are common problems in patients with multiple sclerosis (MS). Urinary incontinence largely affects the physical, social and emotional characteristics and activities of such patients. Objectives: The current study aimed to identify the effect of pelvic floor muscle training on urinary incontinence and its resulting stress, anxiety and depression in patients with MS. Methods: The present clinical trial with a pre-post design was conducted on 50 patients with MS referring to the MS clinic of Imam Khomeini hospital in Tehran, Iran, selected by convenience sampling method. Participants received instructions on pelvic floor muscle exercises and then practiced for three consecutive months. The international consultation on incontinence questionnaireurinary incontinence short form (ICIQ-UI-SF) was used to measure participants' urinary incontinence, and the 21-item depression, anxiety and stress scale (DASS-21) to measure their depression, anxiety and stress, both before the intervention and at the end of the third month of exercising. The obtained data were analyzed by SPSS16 using descriptive statistics and the dependent t test. Results: About 45 (90%) participants practiced pelvic floor muscle exercises until the end of the third month. The frequency and amount of urine leakage and the effect of urinary incontinence on the quality of life differed significantly in the patients after the instructions compared to the status before the intervention (P < 0.001). The mean score of stress (P < 0.001), anxiety (P = 0.04) and depression (P = 0.003) decreased significantly after the intervention. Conclusions: According to the findings, instructing pelvic floor muscle exercises was effective in reducing urinary incontinence and its resulting stress, anxiety and depression in patients with MS. These exercises were recommended as a non-pharmacological, non-invasive and cost-effective method to control urinary incontinence in patients with MS.

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Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease

Cited by 13 publications

References 22 publications

Scattering Month and Day of Baby Delivery in a Retrospective Survey Linked to 1484 Patients With Multiple Sclerosis

Scattering Month and Day of Baby Delivery in a Retrospective Survey Linked to 1484 Patients With Multiple Sclerosis

Effects of Pelvic Floor Muscle Exercises on Urinary Incontinence and Quality of Life in Patients with Multiple Sclerosis

Pelvic Floor Muscle Training Instruction to Control Urinary Incontinence and its Resulting Stress, Anxiety and Depression in Patients with Multiple Sclerosis

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