Abstract:Leptin plays a major role in the regulation of energy intake and energy expenditure, triggering effects on several tissues, such as the hypothalamic-pituitarythyroid axis. The reported effects of leptin on the thyroid are controversial, being mainly explored during energy imbalance. Therefore, the aim of this study was to evaluate the effects of leptin on thyroid function of rats fed ad libitum distinguishing direct leptin responses from those mediated by leptin-dependent suppression of food intake by comparin… Show more
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