Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period

Santos, Daiane S. dos; Boito, Jhonatan P.; Klauck, Vanderlei; Reis, João H.; Gebert, Roger R.; Glombowsky, Patrícia; Biazus, Angelisa H.; Bottari, Nathieli B.; Sousa, Rejane Santos; Machado, Gustavo; Leal, Marta L.R.; Baldissera, Matheus D.; Berwanger, Jean C; Silva, Aleksandro S. Da

doi:10.1590/0001-3765201920171042

An. Acad. Bras. Ciênc.

2019

DOI: 10.1590/0001-3765201920171042

|View full text |Cite

Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period

Daiane S. dos Santos

Jhonatan P. Boito

Vanderlei Klauck

et al.

Abstract: How to cite: SANTOS DS ET AL. 2019. Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period. An Acad Bras Cienc 91: e20171042.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 31 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring

Rodrigues,

Parmeggiani,

Leal

et al. 2023

Animals

View full text Add to dashboard Cite

This study aimed to assess the impact of prepartum maternal diphenyl diselenide (PhSe)2 supplementation on the development, biochemical, immune, and antioxidant parameters of calves. Eighteen Holstein breed calves were used, born to females who were or were not subjected to supplementation, at 42, 28, and 14 days prior to calving. The (PhSe)2 group (DDG) was administered 3 μmol/kg of (PhSe)2 in 4 mL of dimethyl sulfoxide (DMSO), while the DMSO and NaCl groups were administered 4 mL of DMSO and 0.9% NaCl, subcutaneously. The calves were evaluated based on their weight, withers height, body condition score 24 h post-birth (0), as well on days 14, 28, 42, 56, 70. Blood samples were also taken to determine serum variables. Calves on the DDG showed higher average levels of total protein, albumin, and globulins on day 0, and the immunoglobulin G level was significantly higher than the other groups on days 0, 14, 56, 70. Maternal supplementation showed immunomodulatory effect on calves, evidenced by the exceptional rates of passive immunity transfer, as well as the enhancement of humoral immunity. Our research offers fresh insights into the immunomodulatory potential of (PhSe)2, making it a viable alternative in facing this challenging phase, rearing dairy calves.

show abstract

Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring

Rodrigues,

Parmeggiani,

Leal

et al. 2023

Animals

View full text Add to dashboard Cite

show abstract

Efeito metafilático do disseleneto de difenila (PhSe)2 na saúde de bezerras de corte submetidas ao desmame convencional

Parmeggiani,

Rodrigues,

Engelmann

et al. 2024

Sem. Ci. Agr.

View full text Add to dashboard Cite

O objetivo do trabalho foi avaliar o efeito do disseleneto de difenila (PhSe)2, no ganho médio diário, parâmetros bioquímicos e status oxidativo de bezerras de corte submetidas ao desmame convencional. Foram utilizadas 30 bezerras, com seis meses de vida e 152,42±13,75 kg de peso corporal. Foi utilizado um delineamento inteiramente casualizado sendo as unidades experimentais distribuídas em três grupos: grupo controle (GC, n=10): 2 mL de solução de NaCl; grupo dimetilsulfóxido (GDMSO, n=10): 2 mL de dimetilsulfóxido; e grupo disseleneto de difenila (GDD, n=10): 3 µmol kg-1 de (PhSe)2 diluído em 2 mL de dimetilsulfóxido. As coletas e avaliações foram realizadas no M1=basal (-28) e M2 (-14) dia antes do desmame, M3 (0) dia inicial do desmame, M4 (14) e M5 (28) dia após o desmame. Os tratamentos foram administrados no M1, M2 e M3 pela via subcutânea. Todos os animais foram submetidos a condições similares de manejo e alimentação ao decorrer do experimento, tendo livre acesso a água. Os parâmetros avaliados foram: ganho médio diário, proteína total, albumina, globulina, relação albumina:globulina, glutationa reduzida, substâncias reativas ao ácido tiobarbitúrio e capacidade antioxidante total, determinada pelo potencial antioxidante redutor férrico. Dentre os parâmetros avaliados observou-se efeito significativo (P<0,05): no ganho médio diário entre momentos; na albumina entre tratamentos, momentos e interação tratamento x momento; nas globulinas entre momentos e interação tratamento x momento; na relação albumina:globulina entre momentos e interação tratamento x momento; na glutationa reduzida entre momentos e interação tratamento x momento e no potencial antioxidante redutor férrico entre momentos. A administração de disseleneto de difenila em bezerras de corte proporcionou incremento nas variáveis albumina, globulina, relação albumina:globulina e glutationa reduzida durante o desmame convencional, sendo o efeito benéfico do disseleneto de difenila constatado a partir das interações entre tratamento x momentos. Esses resultados demostram que o disseleneto de difenila é uma alternativa as fontes tradicionais de selênio orgânico, e quando utilizado reduziu os desafios vivenciados pelas bezerras de corte durante o desmame convencional.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

334 Leonard St

Brooklyn, NY 11211

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period

Abstract: How to cite: SANTOS DS ET AL. 2019. Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period. An Acad Bras Cienc 91: e20171042.

Cited by 2 publications

References 31 publications

Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring

Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring

Efeito metafilático do disseleneto de difenila (PhSe)2 na saúde de bezerras de corte submetidas ao desmame convencional

Contact Info

Product

Resources

About