Spray-dried porcine plasma added to diets contaminated with aflatoxins and fumonisins shows beneficial effects to piglet health

Abstract

This study was aimed to analyze the effects of spray-dried porcine plasma (SDPP) on the health of post weaning piglets challenged with diets contaminated with aflatoxins and fumonisins. Fifty-six male piglets (7.15 ± 0.61 kg) were allocated in four groups: CTL group received a regular diet; SDPP group received a regular diet and 6% SDPP; MYC group received a diet containing 300 µg/kg aflatoxins and 8,000 µg/kg fumonisins; group MYC+SDPP received 300 µg/kg aflatoxins, 8,000 µg/kg fumonisins and 6% SDPP. The animals that received the experimental diet containing mycotoxins (MYC group) had lower weight gain at the end of the experiment compared to the other treatments. Animals receiving SDPP showed decreased urea levels throughout the experiment (P<0.05). Animals from MYC group presented an increased on reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS) levels and decreased catalase activity (P<0.05). In contrast, SDPP prevented the increase of ROS and TBARS and stimulated superoxide dismutase activity (P<0.05). In conclusion, diet contaminated with mycotoxins (group MYC) caused subclinical intoxication in the piglets, as observed by the increase on free radical's production and lipid peroxidation. Conversely, SDPP presented a protective effect, minimizing the effects of oxidative stress caused by aflatoxins and fumonisins ingestion.

Effect of Spray-Dried Porcine Plasma in Peripartum Sow Feed on Subsequent Litter Size

“…Reproductive performance can vary by individual sow within the same farm, especially in hot climates [41].…”

Application of spray‐dried blood plasma as a feed additive for the replacement of antibiotics in growing‐finishing swine

“…In this study, there was a health challenge in the growth phase, where the agent identified was Glaesserella parasuis, which causes lung lesions such as suppurative bronchopneumonia in addition to polyserositis and polyarthritis. 16 Müller et al 37 evaluated the effect of blood plasma on the health of postweaning piglets challenged with diets contaminated with aflatoxins and fumonisins. Since the diet was contaminated with mycotoxins, it caused subclinical intoxication in piglets, as observed by increased production of free radicals and lipid peroxidation; on the other hand, blood plasma showed a protective effect, minimizing the effects of oxidative stress caused by the ingestion of aflatoxins and fumonisins.…”

Development of livestock feed additives using porcine blood cells

“…Porcine blood makes up the greatest portion among livestock blood that is discarded in Korea (Jeon, 2015). To date, many studies have effectively utilized slaughterhouse blood, mainly the plasma in some countries; however, blood cells have been underutilized (Beski et al, 2015; Müller et al, 2018).…”

“…Porcine blood makes up the greatest portion among livestock blood that is discarded in Korea (Jeon, 2015). To date, many studies have effectively utilized slaughterhouse blood, mainly the plasma in some countries; however, blood cells have been underutilized (Beski et al, 2015;Müller et al, 2018). Slaughterhouse blood contains not only nutritionally valuable constituents (Przybylski et al, 2020) but also biologically active substances with antibacterial activities (Pérez-Bosque et al, 2016), which play an important role in the immunomodulation of animals when used as a feed additive (Nickerson et al, 2019).…”