Malignant Pleural Mesothelioma

Pistolesi, Massimo; Rusthoven, James J.

doi:10.1378/chest.126.4.1318

Cited by 113 publications

(24 citation statements)

References 81 publications

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“…Many physicians have reported little in the way of effective treatment [36][37][38][39] . However, new and more effective chemotherapeutic agents, newer surgical techniques, and emerging new modalities (such as immunotherapy and gene therapy), may usher in new hope for sufferers of this disease 40) . For example, in the treatment of peritoneal mesothelioma, some centers have used Continuous Hyperthermic Peritoneal Perfusion plus chemotherapy and/or cytoreductive surgery with dramatically improved survivals [41][42][43] .…”

Section: Discussionmentioning

confidence: 99%

Malignant Mesothelioma: A Clinical Study of 238 Cases

Haber¹,

Haber

2011

Ind Health

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Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. An estimated 2,500 to 3,000 cases are diagnosed each year in the United States. Although there are individual case reports and small series detailing the clinical aspects of mesothelioma, few studies examine a large series of patients with malignant mesothelioma from the clinical perspective. This study reports on the findings of 238 cases of malignant mesothelioma from a private consultative medical practice. Most cases had a history of occupational asbestos exposure. The mean latency was 48.5 yr, with women having a longer latency than men. The mean age at diagnosis was 70. Survival overall was poor (mean 8.8 months), but treatment was beneficial (mean 11.3 versus 6.4 months). Epithelioid histology conferred a survival advantage over sarcomatoid and responded better to treatment. Our data support an inverse relationship between asbestos dose and latency.

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Section: Discussionmentioning

confidence: 99%

Malignant Mesothelioma: A Clinical Study of 238 Cases

Haber¹,

Haber

2011

Ind Health

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“…Numerose sono le casistiche di MPM riportate in letteratura [5,6,[9][10][11][12][13][14][15][16][17][18] con risultati spesso sconfortanti ai fini dell'incremento della media della sopravvivenza sia nei pazienti tients, survival was 1-3 years longer than average. On this issue, it is worth noting two particularly unfortunate cases of very short survival after surgery despite the fact that surgery was absolutely indicated given the patients' positive response to chemotherapy and radiotherapy.…”

Section: Discussionementioning

confidence: 99%

Imaging before and after multimodal treatment for malignant pleural mesothelioma

et al. 2006

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CT, PET and CT-PET are indicated for diagnosis and, above all, for staging of MPM, in the selection of patients who might benefit from surgery after neoadjuvant therapy and also in identifying small recurrences and/or remote metastases. Being highly specific, PET is essential in the follow-up of patients undergoing chemoradiotherapy alone and/or surgery. Each imaging modality has its advantages and limitations, but their combined use is crucial in determining the most appropriate treatment options for patients with MPM.

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“…Bu olgularda mezotelyomanın progresyonuna bağlı respiratuar yetmezlik veya enfeksiyona bağlı ölüm gerçekleşir (8,11).…”

Section: Paraneoplastik Sendromlara Bağlı Semptomlarunclassified

“…Ağrı, mezotelyomada sık saptanan bir semptom olup genellikle hastalığın geç evrelerinde görülür (4,10,11). Bu ağrı genellikle plöretik tarzdadır (6).…”

Section: Introductionunclassified

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Clinical Assessment and Variations in Clinical Presentation At

Şenyiğit¹

2011

Plev Bult

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Mezotelyoma plevra, perikard, periton ve tunica vaginalis testisin mezotelyumundan kaynaklanan sinsi başlangıçlı bir tümördür. Yüzde seksen oranında plevradan kaynaklanır. Tümörün en büyük sebebi asbest temasıdır (1-3). Klinik seyir ve komplikasyonlarGenellikle mesleki asbest temasının olduğu ülke-lerde daha ziyade erkeklerde görülürken çevresel asbest teması durumunda kadın erkek oranı birbirine eşittir (4, 5). Mesleki asbest temasına bağlı mezotelyo-

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Malignant Pleural Mesothelioma

Cited by 113 publications

References 81 publications

Malignant Mesothelioma: A Clinical Study of 238 Cases

Malignant Mesothelioma: A Clinical Study of 238 Cases

Imaging before and after multimodal treatment for malignant pleural mesothelioma

Clinical Assessment and Variations in Clinical Presentation At

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