Hypocitraturia as a biomarker of renal tubular acidosis in patients with Sjögren’s disease
Rafael Coradin,
Maria Lúcia Lemos Lopes,
João Carlos Goldani
et al.
Abstract:Introduction
Sjögren’s disease (SD) is an immune-mediated chronic inflammatory disease that affects epithelial tissues, mainly salivary and lacrimal glands. It also presents extraglandular manifestations. The main renal manifestation is tubulointerstitial nephritis (TIN), which can manifest as renal tubular acidosis (RTA). Urinary citrate may be a biomarker of RTA in these patients. The objective of this study was to evaluate whether hypocitraturia is a predictive biomarker of RTA in a sample o… Show more
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