Systemic and local antiinflammatory effect of magnesium chloride in experimental arthritis
Ana Carolina Matias Dinelly Pinto,
Rodolfo de Melo Nunes,
Waleska Vidal de Freitas Carvalho
et al.
Abstract:Objective
Despite some knowledge gaps in scientific evidence, MgCl2 is largely used for pain relief in musculoskeletal diseases. Mg salts were shown to provide analgesia postoperatively in orthopedic surgery and low Mg levels were linked to arthritis development and severity. We determined the anti-inflammatory activity of MgCl2 in an acute arthritis model.
Methods
Mice received 0.1 mg/25µL Zymosan (Zy) or saline into the knees. Joint pain was eval… Show more
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