“…Our study reported serum level of YKL-40 was associated with disease activities, including cutaneous disease activity (r = 0.509, p < 0.001), gastrointestinal disease activity (r = 0.381, p = 0.002), cardiovascular disease activity (r = 0.329, p = 0.008), and muscle disease activity (r = 0.425, p < 0.001), and was related to several laboratory indicators, such as CRP (r = 0.303, p = 0.043), CK (r = 0.263, p = 0.037), LDH (r = 0.460, p < 0.001), and HBDH (r = 0.435, p < 0.001), which were consistent with the reports reported by Gao 2019, Jiang 2019, and Hozumi et al that YKL-40 had relationships with MYOACT (r = 0.64, p < 0.01), CRP (r = 0.34, p < 0.01; r = 0.332, p = 0.001), ESR (r = 0.61, p < 0.01; r = 0.251, p = 0.011), KL-6 (r = 0.33, p < 0.01), and ferritin (r = 0.61, p < 0.01; r = 0.46, p < 0.001) [11][12][13]. However, this is not con rmed by the results reported by Carboni 2021 et al [10]. Those uncosistent results might be explained by the fact that study population was small, patients were from different study groups, and patients were with different subgroup diagnosis.…”