Letter to the editor re: prevalence, demographics, and clinical characteristics of Latin American patients with spondyloarthritis

García-Salinas, Rodrigo; Scarafia, Santiago; Sommerfleck, F.

doi:10.1186/s42358-021-00185-5

Cited by 1 publication

(2 citation statements)

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“…The multiplicity of data present at the time of diagnosis and the characteristics of the biological treatment per year add important information to the initiatives of Latin America to respond to challenges in the field of SpA, such as real-world evidence and the development of centers of excellence. 34,35 In conclusion, in our cohort, half of the patients with axSpA were nr-axSpA at the time of diagnosis, with no differences found in terms of clinical characteristics, disease activity, functional capacity, or treatment at 1 year. The only differences found were the fact that patients with AS had a longer delay to diagnosis and the higher proportion of men.…”

Section: Ta B L E 2 (Continued)mentioning

confidence: 61%

“…However, the structured and complete evaluation in terms of clinical, laboratory, and imaging features for all the patients allows for a comprehensive characterization with complete data, in patients with and without radiological involvement alike and may be considered as a strength for this study. The multiplicity of data present at the time of diagnosis and the characteristics of the biological treatment per year add important information to the initiatives of Latin America to respond to challenges in the field of SpA, such as real‐world evidence and the development of centers of excellence 34,35 …”

Section: Discussionmentioning

confidence: 99%

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Non‐radiographic axial spondyloarthritis in South America. Burden of disease and differential features with respect to ankylosing spondylitis at time of diagnosis. A comprehensive analysis with a focus on images

et al. 2022

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Background: Non-radiographic axial spondyloarthritis (nr-axSpA) data from South America are scarce, especially regarding image features. ObjectiveTo estimate the frequency of nr-axSpA and ankylosing spondylitis (AS) in a cohort of Argentinian patients with chronic low back pain (LBP) and to analyze the difference between both, with focus on magnetic resonance imaging (MRI) lesions, at diagnosis. Methods:Patients with LBP and a diagnosis of axSpA who participated in a reumacheck program were included. All patients with a suspicion of SpA were evaluated using blood analytics, HLA-B27, and images (MRI). Sociodemographic data, SpA features, diagnostic dela,y and clinimetrics were assessed by an operator who was blinded to the patient's test results. On MRI, the presence of SpA lesions was assessed and a concordance exercise was carried out between rheumatologists and radiologist.Result: Of 198 LBP patients, 97 had axSpA, 54% of whom were nr-axSpA. A positive MRI was found in 50%. No difference in terms of disease activity, functional impact, laboratory or treatments between nr-axSpA and AS were found. Higher frequencies of male sex and chronic lesions on sacroiliac MRI were found in AS patients. In the logistic regression, an independent association with AS diagnosis was found: male (odds ratio [OR] 4.8), MRI fat replacement (OR 4.6), MRI sclerosis (OR 7.6), and diagnostic delay of more than 2 years (OR 10). The concordance between rheumatologists and radiologists was considered good to very good (κ 0.7-0.8). Conclusion:The frequency of nr-axSpA was 54%. We found a higher frequency of being male, more SpA features, and a longer diagnostic delay in patients with AS.Patients with AS had more structural lesions, with a good concordance between rheumatologist and radiologist.

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Section: Ta B L E 2 (Continued)mentioning

confidence: 61%

Section: Discussionmentioning

confidence: 99%