Molecular detection of Leishmania spp. in road-killed wild mammals in the Central Western area of the State of São Paulo, Brazil

Richini-Pereira, Virgínia Bodelão; Marson, Pâmela Merlo; Hayasaka, Ênio Yoshinori; Victória, Cassiano; Silva, Rodrigo da; Langoni, Hélio

doi:10.1186/1678-9199-20-27

Cited by 24 publications

(27 citation statements)

References 32 publications

(29 reference statements)

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“…Interestingly, some studies found no significant underlying disease in roadkill deer [ 53 ]. Postmortem examination of vehicle-collision cases may be of great value for health population monitoring [ 54 – 56 ]. In Brazil, it is estimated that around 15 animals die per second by vehicle-collision, accounting for more than 470 million animals annually [ 57 ].…”

Section: Discussionmentioning

confidence: 99%

A retrospective pathology study of two Neotropical deer species (1995-2015), Brazil: Marsh deer (Blastocerus dichotomus) and brown brocket deer (Mazama gouazoubira)

et al. 2018

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This retrospective study describes the biological and epidemiological aspects, gross and microscopical findings, and most likely causes of death (CD) in two species of Neotropical deer in Brazil. The animals were collected between 1995 and 2015 and represented 75 marsh deer (MD) and 136 brown brocket deer (BBD). Summarized, pneumonia was diagnosed microscopically in 48 MD and 52 BBD; 76 deer suffered trauma, involving dog attack (14 BBD) and vehicle-collision (14 BBD). Pulmonary edema (50 MD; 55 BBD) and congestion (57 MD; 78 BBD) were the most common findings for both species. Additionally, we diagnosed ruminal and myocardial mycosis in MD and BBD, respectively; ovarian dysgerminoma and pancreatic trematodiasis in BBD; and lesions suggestive of malignant catarrhal fever and orbiviral hemorrhagic disease in both species. The main CD in MD was: respiratory (41/75), alimentary, nutritional, trauma and euthanasia (3/75 each). Correspondingly, in BBD were: trauma (34/131), respiratory (30/131) and euthanasia (9/131). Respiratory disease was often defined by pulmonary edema and pneumonia. We provide evidence that respiratory disease, mainly pneumonia, is a critical pathological process in these Neotropical deer species. Although no etiological agents were identified, there is evidence of bacterial and viral involvement. Our results show trauma, mainly anthropogenic, as a common ailment in BBD. We propose to prioritize respiratory disease in future research focused on South American deer health aspects. We believe anthropogenic trauma may be a primary threat for populations of BBD.

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Section: Discussionmentioning

confidence: 99%

A retrospective pathology study of two Neotropical deer species (1995-2015), Brazil: Marsh deer (Blastocerus dichotomus) and brown brocket deer (Mazama gouazoubira)

et al. 2018

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“…rattus can be found in the domicile (BRANDÃO-FILHO et al, 2003;QUARESMA et al, 2011), in the peridomicile Leishmania in synanthropic rodents (BRANDÃO-FILHO et al, 2003;FERREIRA et al, 2015), in waste areas (VLADIMIR et al, 2015), in rural areas (ALEXANDER et al, 1998;BRANDÃO-FILHO et al, 2003;QUARESMA et al, 2011;FERREIRA et al, 2015), and in wild areas (RICHINI-PEREIRA et al, 2014;ZANET et al, 2014). Because of this adaptability, this rat species may be the link between sylvatic and peridomestic transmission cycles of leishmaniosis (BRANDÃO-FILHO et al, 2003;ANDRADE et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Leishmania in synanthropic rodents (Rattus rattus): new evidence for the urbanization of Leishmania (Leishmania) amazonensis

Caldart

Freire

Ferreira

et al. 2017

Rev. Bras. Parasitol. Vet.

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Leishmania in synanthropic rodents (Rattus rattus):new evidence for the urbanization of Leishmania (Leishmania) amazonensis AbstractThis study aimed to detect parasites from Leishmania genus, to determine the prevalence of anti-Leishmania spp. antibodies, to identify circulating species of the parasite, and to determine epidemiological variables associated with infection in rats caught in urban area of Londrina, Paraná, Brazil. Animal capture was carried out from May to December 2006, serological and molecular methods were performed. DNA was extracted from total blood, and nested-PCR, targeting SSu rRNA from Leishmania genus, was performed in triplicate. The positive samples were sequenced twice by Sanger method to species determination. In total, 181 rodents were captured, all were identified as Rattus rattus and none showed clinical alterations. Forty-one of the 176 (23.3%) animals were positive for Leishmania by ELISA and 6/181 (3.3%) were positive by IFAT. Nine of 127 tested animals (7.1%) were positive by PCR; seven were identified as L.

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“…To the best of our knowledge, this is the first report of fatty liver disease in an armadillo suggests an acute infectious process with lymphoid system involvement. Armadillos are endangered animals, which have been heavily exploited for hunting, food and popular culture, and at the same time are involved in numerous cases of zoonosis (Richini-Pereira et al, 2014, Elsayed et al, 2015. Clinical case reports describing spontaneous pathological states in these animals are key for the improvement of natural and, when necessary, captivity environments, for both the conservation of these species and the development of zoonosis-related research.…”

Section: Resultsmentioning

confidence: 99%

Hepatic steatosis in six-banded armadillo (Euphractus sexcinctus Linnaeus, 1758)

et al. 2018

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The six-banded armadillo (Euphractus sexcinctus) stands out among wild mammals due to the rare occurrence of spontaneous metabolic diseases. When altered, the liver, which is important in metabolism, may trigger a dysfunctional cascade, leading to hepatic steatosis. Here we describe a case of hepatic steatosis in a six-banded armadillo living in captivity. The female specimen was captured and donated to the Federal University of Piaui under SISBIO authorization nº53303. The animal was first referred for a veterinary clinical evaluation, and then euthanized following the ethical standards of the Federal Council of Veterinary Medicine. At the start of the dissection, the abdominal cavity was accessed and sections of all ex situ liver lobes, spleen and mandibular lymph node were subjected to routine histological processing; the results were photo documented. The anatomic and histopathological analysis confirmed the diagnosis of hepatic steatosis, which we propose is related to an infectious process as a result of the changes observed in the organs of the lymphoid system. This report of fatty liver disease in armadillo suggests an acute infectious process with lymphoid system involvement. Keywords: Euphractus sexcinctus, infectious, liver, six-banded armadillo, steatosis. Esteatose hepática em tatu-peba (Euphractus sexcinctus Linnaeus, 1758)Resumo: O tatu-verdadeiro (Euphractus sexcinctus) se destaca entre os mamíferos selvagens devido à rara ocorrência de doenças metabólicas espontâneas. Quando alterado, o fígado, que é importante no metabolismo, pode desencadear uma cascata disfuncional, levando a esteatose hepática. Foi descrito um caso de esteatose hepática em um tatu-verdadeiro vivendo em cativeiro. O espécime feminino foi capturado e doado para a Universidade Federal do Piauí sob a autorização SISBIO nº53303. O animal foi encaminhado para uma avaliação clínica veterinária e, depois, submetido à eutanásia seguindo os padrões éticos do Conselho Federal de Medicina Veterinária. No início da dissecção, acessou-se a cavidade abdominal e as seções de todos os lóbulos do fígado ex situ, do baço e do linfonodo mandibular foram submetidos ao processamento histológico de rotina. Os resultados foram fotomicrografados e documentados. A análise anatômica e histopatológica confirmou o diagnóstico de esteatose hepática, que está relacionada a um processo infeccioso como resultado das mudanças observadas nos órgãos do sistema linfóide. Este relatório de doença hepática gordurosa no armadillo sugere um processo infeccioso agudo com comprometimento do sistema linfático. Euphractus sexcinctus, infecção, fígado, tatu-verdadeiro, esteatose. Palavras-chaves:

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Molecular detection of Leishmania spp. in road-killed wild mammals in the Central Western area of the State of São Paulo, Brazil

Cited by 24 publications

References 32 publications

A retrospective pathology study of two Neotropical deer species (1995-2015), Brazil: Marsh deer (Blastocerus dichotomus) and brown brocket deer (Mazama gouazoubira)

A retrospective pathology study of two Neotropical deer species (1995-2015), Brazil: Marsh deer (Blastocerus dichotomus) and brown brocket deer (Mazama gouazoubira)

Leishmania in synanthropic rodents (Rattus rattus): new evidence for the urbanization of Leishmania (Leishmania) amazonensis

Hepatic steatosis in six-banded armadillo (Euphractus sexcinctus Linnaeus, 1758)

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