Epidemic Neuromyasthenia: Outbreak among Nurses at a Children's Hospital

Antibody to Coxsackie B virus in diagnosing postviral fatigue syndrome.

“…A total of 5639 (21%) men and 3307 (12%) women died during the follow up period, in whom death in 3052 (54%) men and 1368 (41%) women was from cardiovascular causes. During short (0-6 years), medium (7-13 years), and long (14)(15)(16)(17)(18)(19)(20) years) term follow up the relative risk of death from cardiovascular disease increased with increasing serum sialic acid concentration. The relative risk (95% confidence interval) associated with the highest quartile of sialic acid concentration compared with the lowest quartile was 2-38 (2-01 to 2.83) in men and (1-93 to 3.57) in women.…”

Differential Diagnosis

“…The disease, called by some the ''Royal Free Disease,'' was similar in its clinical pattern to outbreaks which had been encountered in health staff populations of other hospitals including the Los Angeles County General Hospital in 1934 (4), The Middlesex Hospital in London in 1952 (5), the Addington Hospital in Durban in South Africa (6) and at my own alumnus, the Hospital for Sick Children at Great Ormond Street, London, over a six month period from August 1970 (7).…”

Chronic Fatigue: A Survey, Outcome Study and Proposals

“…Comparisons with adult CFS (Butler et al, 1991; Dillon et al, 1974; Dowsett et al, 1990; Escobar et al, 1989; Wessely & Powell, 1989) reveal that both child and adult CFS comprise a range of symptoms and share some high‐ranking symptoms: headache, aches and pains, and hypersomnia/insomnia. Decreased appetite was prevalent in the children in the current study, but was noticeably not stated in the adult studies.…”