Intercropping is used to increase grain production in many areas of the world. However, this increasing crop yield costs large amounts of water used by intercropped plants. In addition, intercropping usually requires higher inputs that induce greenhouse gas emissions. Actually, it is unknown whether intercropping can be effective in waterlimited arid areas. Here, we measured crop yield, water consumption, soil respiration, and carbon emissions of wheatmaize intercropping under different tillage and crop residue management options. . Reduced tillage decreased C emission over conventional tillage by 6.7 % for the intercropping, 5.9 % for monoculture maize, and 7.1 % for monoculture wheat. Compared to monoculture maize, wheat-maize intercropping used more water but emitted 3.4 kg C per hectare per millimeter of water used, which was 23 % lower than monoculture maize. Overall, our findings show that maize-wheat intercropping with reduced tillage coupled with stubble mulching can be used to increase grain production while effectively lower carbon emissions in arid areas.