Preparation and properties of fluorescent quantum dots microbeads encapsulated in-situ by polyisobornyl methacrylate for immunochromatography

Jin, Siyang; Lin, Leping; Chen, Xiaohui; Liu, Fan; Zhu, Xiaogang; Yan, Guoping

doi:10.1117/1.jnp.15.016008

Cited by 5 publications

(2 citation statements)

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“…QDs are nanoscale, low-dimensional semiconductor materials that have attracted attention with their desirable optical properties, such as broad excitation spectrum, narrow symmetric emission spectrum, precise tunability of emission peak, long fluorescence lifetime, photochemical stability, and negligible photobleaching [ [138] , [139] , [140] ]. QDs-ICA employs QDs as readout signals to increase sensitivity, which benefits from both ICA and QDs [ 46 , 127 , 141 , 142 ].…”

Section: Luminescence Immunoassays On Microfluidic Chipsmentioning

confidence: 99%

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

Yuan¹,

Chen²,

Wan³

et al. 2022

TrAC Trends in Analytical Chemistry

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Section: Luminescence Immunoassays On Microfluidic Chipsmentioning

confidence: 99%

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

Yuan¹,

Chen²,

Wan³

et al. 2022

TrAC Trends in Analytical Chemistry

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“…So, it is used as a biodegradable polymeric carrier in biomedical applications [ 23 , 24 ]. In previous works, dextran-containing gadolinium complexes were shown to have a greatly enhanced magnetic resonance imaging (MRI) contrast between normal and diseased popliteal lymph nodes, while providing a prolonged duration of stay in the lymphatic system in rabbits [ 25 , 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Dextran Fluorescent Probes Containing Sulfadiazine and Rhodamine B Groups

et al. 2022

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Fluorescent imaging has been expanded, as a non-invasive diagnostic modality for cancers, in recent years. Fluorescent probes in the near-infrared window can provide high sensitivity, resolution, and signal-to-noise ratio, without the use of ionizing radiation. Some fluorescent compounds with low molecular weight, such as rhodamine B (RhB) and indocyanine green (ICG), have been used in fluorescent imaging to improve imaging contrast and sensitivity; however, since these probes are excreted from the body quickly, they possess significant restrictions for imaging. To find a potential solution to this, this work investigated the synthesis and properties of novel macromolecular fluorescent compounds. Herein, water-soluble dextran fluorescent compounds (SD-Dextran-RhB) were prepared by the attachment of RhB and sulfadiazine (SD) derivatives to dextran carrier. These fluorescent compounds were then characterized through IR, 1H NMR, 13C NMR, UV, GPC, and other methods. Assays of their cellular uptake and cell cytotoxicity and fluorescent imaging were also performed. Through this study, it was found that SD-Dextran-RhB is sensitive to acidic conditions and possesses low cell cytotoxicities compared to normal 293 cells and HepG2 and HeLa tumor cells. Moreover, SD-Dextran-RhB demonstrated good fluorescent imaging in HepG2 and HeLa cells. Therefore, SD-Dextran-RhB is suitable to be potentially applied as a probe in the fluorescent imaging of tumors.

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Dual-modal polypeptide-containing contrast agents for magnetic resonance/fluorescence imaging

Zheng

Tang

Zhang

et al. 2022

Bioorganic Chemistry

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Preparation and properties of fluorescent quantum dots microbeads encapsulated in-situ by polyisobornyl methacrylate for immunochromatography

Cited by 5 publications

References 0 publications

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

Dextran Fluorescent Probes Containing Sulfadiazine and Rhodamine B Groups

Dual-modal polypeptide-containing contrast agents for magnetic resonance/fluorescence imaging

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