Intracranial compliance in patients with COVID-19: a multicenter observational study
Ana Flávia Silveira,
Marcella Barreto Santos,
Nelci Zanon Collange
et al.
Abstract:Background Patients with severe coronavirus disease-19 (COVID-19) may require the use of invasive mechanical ventilation (MV) for prolonged periods. Aggressive MV parameters have been associated with changes in intracranial pressure (ICP) in patients with acute intracranial disorders. Significant ICP elevation could compromise intracranial compliance (ICC) and cerebrovascular hemodynamics (CVH). However, the effects of these parameters in individuals without neurological disorders have not yet been evaluated.
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