Long-COVID olfactory dysfunction: allele E4 of apolipoprotein E as a possible protective factor
Danilo Nunes Oliveira,
José Wagner Leonel Tavares-Júnior,
Werbety Lucas Queiroz Feitosa
et al.
Abstract:Background Olfactory dysfunction (OD) represents a frequent manifestation of the coronavirus disease 2019 (COVID-19). Apolipoprotein E (APOE) is a protein that interacts with the angiotensin-converting enzyme receptor, essential for viral entry into the cell. Previous publications have suggested a possible role of APOE in COVID-19 severity. As far as we know, no publications found significant associations between this disease's severity, OD, and APOE polymorphisms (E2, E3, and E4).
Objective To analy… Show more
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