Fundamentals of deep brain stimulation for Parkinson's disease in clinical practice: part 2

Abstract

The field of neuromodulation has evolved significantly over the past decade. Developments include novel indications and innovations of hardware, software, and stimulation techniques leading to an expansion in scope and role of these techniques as powerful therapeutic interventions. In this review, which is the second part of an effort to document and integrate the basic fundamentals and recent successful developments in the field, we will focus on classic paradigms for electrode placement as well as new exploratory targets, mechanisms of neuromodulation using this technique and new developments, including focused ultrasound driven ablative procedures.

Tailoring and personalizing deep brain stimulation for Parkinson's disease

“…This gap is in great part responsible for the disproportion between the number of PD patients to which surgery should be offered and the actual number of patients in which the surgery is actually and correctly performed. 2 In this issue of the journal, an article in two parts by Aquino and Moscovich et al 3,4 explored the state-of-the-art and new and future technologies in neuromodulation for PD. The authors reviewed the DBS indication criteria, expected outcomes, and possible targets according to patients' profiles, programming, and medication management.…”

“…In this issue of the journal, an article in two parts by Aquino and Moscovich et al 3 4 explored the state-of-the-art and new and future technologies in neuromodulation for PD. The authors reviewed the DBS indication criteria, expected outcomes, and possible targets according to patients' profiles, programming, and medication management.…”