“…The authors review the current literature on the disease, with an emphasis on treatment with anti-B cell agents. 1 The article on gene-based therapies for neuromuscular disorders, by Zanotelli, França & Marques Jr., clearly discusses the new treatments for genetically caused neuromuscular diseases, in particular the use of therapies with gene regulation, including gene replacement, small interfering RNA (siRNA), and antisense antinucleotides. 2 The review emphasizes the new treatments for motor neuron diseases, neuropathies, and Duchenne muscular dystrophy.…”