HPV Vaccination and Screening with High-Performance Test: Brazilian Evidence

Abstract

Brazil has a critical issue on women's health to solve: one woman dies every 90 minutes due to cervical cancer with a mean age of 45 years. 1 Considered eradicable cancer, there are two established strategies to control it: vaccination against HPV and periodic screening for detection of precancerous lesions. The Brazilian public health system offers both, free of charge, although this is not enough.

Current HPV Vaccination Strategies in Brazil

“…4) Title: HPV Vaccination and Screening with High-Performance Test: Brazilian Evidence. Year of publication: 2021 [11].…”

“…For Texeira et al [11], the parents' difficulty in taking adolescents to be vaccinated at Health Units during business hours may be the main obstacle. A Brazilian study that surveyed 826 parents using an online questionnaire suggested that low coverage appeared to be due to challenges in vaccine administration and barriers to HPV vaccination at health centers rather than vaccine refusal.…”

“…In April 2022, the WHO SAGE (Immunization Strategies Advisory Group) compared the evidence of the efficacy of the single dose of HPV vaccines with evidence of the efficacy of two or three doses in the recommended regimens, and it was concluded that a single dose may offer significant and non-negligible protection against HPV, in some situations, it may be equivalent to the two doses that are currently recommended for adolescents [11]. These observations would also allow the two-dose regimen to be expanded to ages over 14 years.…”