Avaliação do perfil laboratorial de idosos com fratura de fêmur proximal por mecanismo de baixa energia

Aim: To evaluate the prognostic impact at admission of 10 biochemical indices for prediction postoperative myocardial injury (PMI) and/or hospital death in hip fracture (HF) patients. Methods: In 1273 consecutive patients with HF (mean age 82.9 ± 8.7 years, 73.5% women), clinical and laboratory parameters were collected prospectively, and outcomes were recorded. Multiple logistic regression and receiver-operating characteristic analyses (the area under the curve, AUC) were preformed, the number needed to predict (NNP) outcome was calculated. Results: Age ≥ 80 years and IHD were the most prominent clinical factors associated with both PMI (with cardiac troponin I rise) and in-hospital death. PMI occurred in 555 (43.6%) patients and contributed to 80.3% (49/61) of all deaths (mortality rate 8.8% vs.1.9% in non-PMI patients). The most accurate biochemical predictive markers were parathyroid hormone > 6.8 pmol/l, urea > 7.5 mmol/l, 25(OH)vitamin D < 25 nmol/l, albumin < 33 g/l, and ratios gamma-glutamyl transferase (GGT) to alanine aminotransferase > 2.5, urea/albumin ≥ 2.0 and GGT/albumin ≥ 7.0; the AUC for developing PMI ranged between 0.782 and 0.742 (NNP: 1.84–2.13), the AUC for fatal outcome ranged from 0.803 to 0.722, (NNP: 3.77–9.52). Conclusions: In HF patients, easily accessible biochemical indices at admission substantially improve prediction of hospital outcomes, especially in the aged > 80 years with IHD.

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Comparison of Prognostic Value of 10 Biochemical Indices at Admission for Prediction Postoperative Myocardial Injury and Hospital Mortality in Patients with Osteoporotic Hip Fracture

Fisher

Srikusalanukul

Fisher

et al. 2022

JCM

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Fratura de fêmur nos idosos: tempo de espera cirúrgica e desfecho da hospitalização

Alcantara

Dellaroza²,

Ribeiro³

et al. 2021

Cienc. Cuid. Saúde

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Objetivo: Analisar o tempo de espera para correção de fratura de fêmur, seus fatores associados e o desfecho de hospitalização. Método: Transversal exploratório, com a população de idosos ≥60 anos internados por fratura de fêmur no período de 2015 a 2017. Os dados foram coletados através do prontuário físico, comanálises estatísticas considerando o nível de significância estatística de p<0,05. Resultados: Dos idosos estudados, 61,4% correspondem ao sexo feminino. Aqueles que permaneceram por mais do que sete dias à espera de cirurgia se associaram ao tempo de hospitalização maior do que 10 dias, lesão por pressão (p<0,001) e ao desfecho óbito (p=0,003). A média de permanência hospitalar foi de 13,8 dias e do tempo esperadopela cirurgia de 6,6 dias. A espera da realização do risco cirúrgico e vaga em unidade de terapia intensiva foram fatores que provocaram atraso na realização da cirurgia em 23,2% dos idosos. Conclusão: Esperar pela cirurgia por mais de sete dias aumentou o tempo de permanência hospitalar e a taxa de mortalidade. Além disso, a ausência de vaga de terapia intensiva e a espera pelo risco cirúrgico contribuíram para o atraso da cirurgia e seu desfecho.

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Avaliação do perfil laboratorial de idosos com fratura de fêmur proximal por mecanismo de baixa energia

Cited by 2 publications

References 21 publications

Comparison of Prognostic Value of 10 Biochemical Indices at Admission for Prediction Postoperative Myocardial Injury and Hospital Mortality in Patients with Osteoporotic Hip Fracture

Comparison of Prognostic Value of 10 Biochemical Indices at Admission for Prediction Postoperative Myocardial Injury and Hospital Mortality in Patients with Osteoporotic Hip Fracture

Fratura de fêmur nos idosos: tempo de espera cirúrgica e desfecho da hospitalização

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