Clinical Features and Management of Women with Borderline Ovarian Tumors in a Single Center in Brazil

Abstract

Objective The aim of the present study was to describe and analyze data of 57 women with borderline ovarian tumors (BOTs) regarding histological characteristics, clinical features and treatment management at the Department of Obstetrics and Gynecology of the Universidade Estadual de Campinas (Unicamp, in the Portuguese acronym). Methods The present retrospective study analyzed data obtained from clinical and histopathological reports of women with BOTs treated in a single cancer center between 2010 and 2018. Results A total of 57 women were included, with a mean age of 48.42 years old (15.43–80.77), of which 30 (52.63%) were postmenopausal, and 18 (31.58%) were < 40 years old. All of the women underwent surgery. A total of 37 women (64.91%) were submitted to complete surgical staging for BOT, and none (0/57) were submitted to pelvic or paraortic lymphadenectomy. Chemotherapy was administered for two patients who recurred. The final histological diagnoses were: serous in 20 (35.09%) cases, mucinous in 26 (45.61%), seromucinous in 10 (17.54%), and endometrioid in 1 (1.75%) case. Intraoperative analyses of frozen sections were obtained in 42 (73.68%) women, of which 28 (66.67%) matched with the final diagnosis. The mean follow-up was of 42.79 months (range: 2.03–104.87 months). Regarding the current status of the women, 45 (78.95%) are alive without disease, 2 (3.51%) are alive with disease, 9 (15.79%) had their last follow-up visit > 1 year before the performance of the present study but are alive, and 1 patient (1.75%) died of another cause. Conclusion Women in the present study were treated according to the current guidelines and only two patients recurred.

Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases

“…Previous studies have shown that the matched rate between the results of frozen-section and definitive histological examination varies from 66.67 to 88.9% [31,32]. Therefore, it is important for surgeons to counsel patients and their families with regard to possible intraoperative indications.…”

“…The accuracy of frozen-section examination is lower than optimal and the availability of reliable frozen-section analysis methods in many hospitals is difficult. Previous studies have shown that the matched rate between the results of frozen-section and definitive histological examination varies from 66.67 to 88.9% [ 31 , 32 ]. Therefore, it is important for surgeons to counsel patients and their families with regard to possible intra-operative indications.…”

Staging Procedures Fail to Benefit Women with Borderline Ovarian Tumours Who Want to Preserve Fertility: A Retrospective Analysis of 448 cases

“…The accuracy of frozen-section examination is lower than optimal and the availability of reliable frozen-section analysis methods in many hospitals is difficult. Previous studies have shown that the matched rate between the results of frozen-section and definitive histological examination varies from 66.67% to 88.9% [29,30]. Therefore, it is important for surgeons to counsel patients and their families with regard to possible intra-operative indications.…”

Staging Procedures Fail to Benefit to the Fertility-preserved Women with Borderline Ovarian Tumors: A Retrospective Analysis of 448 cases

“…The accuracy of frozen-section examination is lower than optimal and the availability of reliable frozen-section analysis in many hospitals is problematic. Previous studies have shown that the matched rate between frozen-section and definitive histological result varies from 66.67-88.9% [29,30]. Therefore, it is important for surgeons to counsel patients and their families appropriately with regard to intra-operative management.…”